ID   NHAA_RICAH              Reviewed;          68 AA.
AC   A8GQA2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   13-NOV-2007, sequence version 1.
DT   25-MAY-2022, entry version 61.
DE   RecName: Full=Putative Na(+)/H(+) antiporter NhaA homolog;
GN   Name=nhaA; OrderedLocusNames=A1C_06770;
OS   Rickettsia akari (strain Hartford).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; spotted fever group.
OX   NCBI_TaxID=293614;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hartford;
RA   Madan A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S.,
RA   Sanchez A., Whiting M., Dasch G., Eremeeva M.;
RT   "Complete genome sequence of Rickettsia akari.";
RL   Submitted (SEP-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter
CC       family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. This sequence is shorter
CC       than orthologs. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP000847; ABV75577.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8GQA2; -.
DR   SMR; A8GQA2; -.
DR   STRING; 293614.A1C_06770; -.
DR   EnsemblBacteria; ABV75577; ABV75577; A1C_06770.
DR   KEGG; rak:A1C_06770; -.
DR   eggNOG; COG3004; Bacteria.
DR   HOGENOM; CLU_2791307_0_0_5; -.
DR   Proteomes; UP000006830; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.10; -; 1.
DR   InterPro; IPR023171; Na/H_antiporter_dom_sf.
DR   InterPro; IPR004670; NhaA.
DR   PANTHER; PTHR30341; PTHR30341; 1.
DR   Pfam; PF06965; Na_H_antiport_1; 1.
PE   5: Uncertain;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..68
FT                   /note="Putative Na(+)/H(+) antiporter NhaA homolog"
FT                   /id="PRO_0000334395"
FT   TRANSMEM        21..41
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        48..68
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   68 AA;  7603 MW;  E7229C986D891393 CRC64;
     MVVHALIYIF FNYDKPGLIK GWAVPIATDT AFVLGIVSFF SRHISLELRT FIIGFSLIDD
     AFAPIILS