ID   NHAA_RICBR              Reviewed;         132 AA.
AC   Q1RGL5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   16-MAY-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Putative Na(+)/H(+) antiporter NhaA homolog;
GN   Name=nhaA; OrderedLocusNames=RBE_1418;
OS   Rickettsia bellii (strain RML369-C).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Rickettsiaceae; Rickettsieae; Rickettsia; belli group.
OX   NCBI_TaxID=336407;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RML369-C;
RX   PubMed=16703114; DOI=10.1371/journal.pgen.0020076;
RA   Ogata H., La Scola B., Audic S., Renesto P., Blanc G., Robert C.,
RA   Fournier P.-E., Claverie J.-M., Raoult D.;
RT   "Genome sequence of Rickettsia bellii illuminates the role of amoebae in
RT   gene exchanges between intracellular pathogens.";
RL   PLoS Genet. 2:733-744(2006).
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter
CC       family. {ECO:0000305}.
CC   -!- CAUTION: Could be the product of a pseudogene. This sequence is shorter
CC       than orthologs. {ECO:0000305}.
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DR   EMBL; CP000087; ABE05499.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q1RGL5; -.
DR   SMR; Q1RGL5; -.
DR   STRING; 336407.RBE_1418; -.
DR   EnsemblBacteria; ABE05499; ABE05499; RBE_1418.
DR   KEGG; rbe:RBE_1418; -.
DR   eggNOG; COG3004; Bacteria.
DR   HOGENOM; CLU_1915509_0_0_5; -.
DR   Proteomes; UP000001951; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006885; P:regulation of pH; IEA:InterPro.
DR   GO; GO:0006814; P:sodium ion transport; IEA:InterPro.
DR   Gene3D; 1.20.1530.10; -; 1.
DR   InterPro; IPR023171; Na/H_antiporter_dom_sf.
DR   InterPro; IPR004670; NhaA.
DR   PANTHER; PTHR30341; PTHR30341; 1.
DR   Pfam; PF06965; Na_H_antiport_1; 1.
PE   5: Uncertain;
KW   Cell inner membrane; Cell membrane; Membrane; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..132
FT                   /note="Putative Na(+)/H(+) antiporter NhaA homolog"
FT                   /id="PRO_0000334397"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        36..56
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        72..92
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        97..117
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   132 AA;  15014 MW;  E79C3C4423AD4246 CRC64;
     MFISFVIIII LFILNYKQVK HLLYYTIVGV LLWVSMVEAG IHGTLCGAII ALFIPVNIKG
     QINSSFHKLE KLIQPFVNYF ILPLFVFMNS GVLLKDFSFR SVCSSLTFGI ILGLFIGKQL
     RSYAIFLSMR EV