ID   NHE1_BACCE              Reviewed;          91 AA.
AC   P81242;
DT   10-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2000, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Non-hemolytic enterotoxin 105 kDa component;
DE            Short=Nhe;
DE            EC=3.4.24.-;
DE   Flags: Fragment;
OS   Bacillus cereus.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1396;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 41-49, AND PROTEIN SEQUENCE OF 1-40
RP   AND 50-91.
RC   STRAIN=1230-88;
RX   PubMed=10499286; DOI=10.1111/j.1574-6968.1999.tb08699.x;
RA   Lund T., Granum P.E.;
RT   "The 105-kDa protein component of Bacillus cereus non-haemolytic
RT   enterotoxin (Nhe) is a metalloprotease with gelatinolytic and
RT   collagenolytic activity.";
RL   FEMS Microbiol. Lett. 178:355-361(1999).
CC   -!- FUNCTION: This protein is a metalloprotease with gelatinolytic and
CC       collagenolytic activity and is a component of the non-hemolytic
CC       enterotoxin complex (NHE).
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC       Note=Binds 1 zinc ion.;
CC   -!- SUBCELLULAR LOCATION: Secreted.
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DR   AlphaFoldDB; P81242; -.
DR   SMR; P81242; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0008237; F:metallopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Enterotoxin; Hydrolase; Metal-binding;
KW   Metalloprotease; Protease; Secreted; Toxin; Virulence; Zinc.
FT   CHAIN           1..>91
FT                   /note="Non-hemolytic enterotoxin 105 kDa component"
FT                   /id="PRO_0000078244"
FT   NON_TER         91
SQ   SEQUENCE   91 AA;  10412 MW;  F71A76E615253C6C CRC64;
     EEKVPYNVLK TKPVGIEKSV DEVGHISKVD ETLSFQERLK GDFSQRPASI TKKTAVKQVK
     ESYSMADLNK MNDRELVETL GSIKWHQYTD L