ID   NHP2_DROYA              Reviewed;         160 AA.
AC   Q6XIP0; B4PIH4;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 81.
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 2-like protein;
DE   AltName: Full=H/ACA snoRNP protein NHP2;
GN   Name=NHP2; ORFNames=GE20000;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=14525923; DOI=10.1101/gr.1311003;
RA   Domazet-Loso T., Tautz D.;
RT   "An evolutionary analysis of orphan genes in Drosophila.";
RL   Genome Res. 13:2213-2219(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tai18E2 / Tucson 14021-0261.01;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Required for ribosome biogenesis. Part of a complex which
CC       catalyzes pseudouridylation of rRNA. This involves the isomerization of
CC       uridine such that the ribose is subsequently attached to C5, instead of
CC       the normal N1. Pseudouridine ('psi') residues may serve to stabilize
CC       the conformation of rRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the small nucleolar ribonucleoprotein particle
CC       containing H/ACA-type snoRNAs (H/ACA snoRNPs). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL8 family.
CC       {ECO:0000305}.
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DR   EMBL; AY231789; AAR09812.1; -; mRNA.
DR   EMBL; CM000159; EDW94531.1; -; Genomic_DNA.
DR   RefSeq; XP_002094819.1; XM_002094783.2.
DR   AlphaFoldDB; Q6XIP0; -.
DR   SMR; Q6XIP0; -.
DR   STRING; 7245.FBpp0265010; -.
DR   EnsemblMetazoa; FBtr0266518; FBpp0265010; FBgn0068118.
DR   GeneID; 6534135; -.
DR   KEGG; dya:Dyak_GE20000; -.
DR   eggNOG; KOG3167; Eukaryota.
DR   HOGENOM; CLU_084513_1_0_1; -.
DR   OMA; IDVYSHI; -.
DR   OrthoDB; 1538526at2759; -.
DR   PhylomeDB; Q6XIP0; -.
DR   Proteomes; UP000002282; Chromosome 3L.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005732; C:sno(s)RNA-containing ribonucleoprotein complex; ISS:UniProtKB.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0048142; P:germarium-derived cystoblast division; IEA:EnsemblMetazoa.
DR   GO; GO:0031118; P:rRNA pseudouridine synthesis; ISS:UniProtKB.
DR   Gene3D; 3.30.1330.30; -; 1.
DR   InterPro; IPR029064; L30e-like.
DR   InterPro; IPR004038; Ribosomal_L7Ae/L30e/S12e/Gad45.
DR   InterPro; IPR018492; Ribosomal_L7Ae/L8/Nhp2.
DR   Pfam; PF01248; Ribosomal_L7Ae; 1.
DR   PRINTS; PR00881; L7ARS6FAMILY.
DR   SUPFAM; SSF55315; SSF55315; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Ribonucleoprotein; Ribosome biogenesis; RNA-binding;
KW   rRNA processing.
FT   CHAIN           1..160
FT                   /note="H/ACA ribonucleoprotein complex subunit 2-like
FT                   protein"
FT                   /id="PRO_0000136773"
SQ   SEQUENCE   160 AA;  17722 MW;  8FE473CFD992FF71 CRC64;
     MVKVKVERSE DADESVVASG DVTIKEEESY DDKLIFVNAI AKPMAGKKLA KKCYKLVKKA
     MKHKTFLRNG LKDVQTRLRK GETGICIFAG DVTPVDIMCH LPAVCEEKGI PYAYTPSRAD
     LGAAMGVKRG TVALLVRQND EYKDLYDEVK EELSALNIPV