ID   NHR51_CAEEL             Reviewed;         371 AA.
AC   O17927;
DT   21-FEB-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 3.
DT   03-AUG-2022, entry version 140.
DE   RecName: Full=Nuclear hormone receptor family member nhr-51;
GN   Name=nhr-51; ORFNames=K06B4.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- FUNCTION: Orphan nuclear receptor.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC   -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC       {ECO:0000305}.
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DR   EMBL; Z83233; CAB05760.3; -; Genomic_DNA.
DR   PIR; T23364; T23364.
DR   RefSeq; NP_506898.2; NM_074497.4.
DR   AlphaFoldDB; O17927; -.
DR   SMR; O17927; -.
DR   BioGRID; 45045; 2.
DR   DIP; DIP-25072N; -.
DR   IntAct; O17927; 2.
DR   STRING; 6239.K06B4.1; -.
DR   PaxDb; O17927; -.
DR   EnsemblMetazoa; K06B4.1.1; K06B4.1.1; WBGene00003641.
DR   GeneID; 180052; -.
DR   KEGG; cel:CELE_K06B4.1; -.
DR   UCSC; K06B4.1; c. elegans.
DR   CTD; 180052; -.
DR   WormBase; K06B4.1; CE35582; WBGene00003641; nhr-51.
DR   eggNOG; KOG3575; Eukaryota.
DR   GeneTree; ENSGT00970000195839; -.
DR   HOGENOM; CLU_007368_3_0_1; -.
DR   InParanoid; O17927; -.
DR   OMA; AHEWAFL; -.
DR   OrthoDB; 1425518at2759; -.
DR   PhylomeDB; O17927; -.
DR   PRO; PR:O17927; -.
DR   Proteomes; UP000001940; Chromosome V.
DR   Bgee; WBGene00003641; Expressed in larva.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 1.10.565.10; -; 1.
DR   Gene3D; 3.30.50.10; -; 1.
DR   InterPro; IPR035500; NHR-like_dom_sf.
DR   InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR   InterPro; IPR001628; Znf_hrmn_rcpt.
DR   InterPro; IPR013088; Znf_NHR/GATA.
DR   Pfam; PF00104; Hormone_recep; 1.
DR   Pfam; PF00105; zf-C4; 1.
DR   PRINTS; PR00047; STROIDFINGER.
DR   SMART; SM00430; HOLI; 1.
DR   SMART; SM00399; ZnF_C4; 1.
DR   SUPFAM; SSF48508; SSF48508; 1.
DR   PROSITE; PS51843; NR_LBD; 1.
DR   PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW   Transcription; Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           1..371
FT                   /note="Nuclear hormone receptor family member nhr-51"
FT                   /id="PRO_0000223577"
FT   DOMAIN          98..337
FT                   /note="NR LBD"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT   DNA_BIND        2..77
FT                   /note="Nuclear receptor"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT   ZN_FING         5..25
FT                   /note="NR C4-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT   ZN_FING         41..60
FT                   /note="NR C4-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ   SEQUENCE   371 AA;  43306 MW;  4C8F3CA85C004ACE CRC64;
     MNKNCLICHR KAAGQHYGVL SCFACKMFFH RMVVENLHYC CQKFNKCYEK FIILPKCKAC
     RYQKCLEMGM QAFPRRVKSF EESMDLKIQR MLMNLSEMDE QRHWRMLNSY SIEDPSLGDV
     LVDSNVMKIM RKPSNQKVTA HEWAFLDVYS RISHFSNFEF MNNISFADRK LIFSFNCLRT
     GVFHGSMRTL REQRDCLLTP SGEDVYPDAV HNLFKDSPGL LNRTCCLLVS KLIELKVTNE
     EYQLLSLIFF CNPTISHNLS DFARNTLASH QIKYSSALFR HLQITNPGTA PVRFQELISL
     VHVINRVTND MQHVSMMFQC MIPSFKFKQL VTDTFVDCGV VQKKSNVKIL NEKPCADSSQ
     DFIFHKNKFI H