NHR96_CAEEL
ID NHR96_CAEEL Reviewed; 402 AA.
AC Q95X91;
DT 15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Nuclear hormone receptor family member nhr-96;
GN Name=nhr-96; ORFNames=F44C8.11;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; FO081357; CCD71014.1; -; Genomic_DNA.
DR RefSeq; NP_503611.3; NM_071210.4.
DR AlphaFoldDB; Q95X91; -.
DR BioGRID; 43764; 1.
DR DIP; DIP-25507N; -.
DR STRING; 6239.F44C8.11; -.
DR EPD; Q95X91; -.
DR PaxDb; Q95X91; -.
DR EnsemblMetazoa; F44C8.11.1; F44C8.11.1; WBGene00003686.
DR GeneID; 178703; -.
DR KEGG; cel:CELE_F44C8.11; -.
DR UCSC; F44C8.11; c. elegans.
DR CTD; 178703; -.
DR WormBase; F44C8.11; CE35309; WBGene00003686; nhr-96.
DR eggNOG; KOG3575; Eukaryota.
DR GeneTree; ENSGT00970000195928; -.
DR HOGENOM; CLU_007368_7_1_1; -.
DR InParanoid; Q95X91; -.
DR OrthoDB; 1136195at2759; -.
DR PhylomeDB; Q95X91; -.
DR PRO; PR:Q95X91; -.
DR Proteomes; UP000001940; Chromosome V.
DR Bgee; WBGene00003686; Expressed in pharyngeal muscle cell (C elegans) and 3 other tissues.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..402
FT /note="Nuclear hormone receptor family member nhr-96"
FT /id="PRO_0000053800"
FT DOMAIN 154..402
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 4..79
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 7..27
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 44..67
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 402 AA; 46145 MW; C81D3606A3979F3A CRC64;
MLSFGLCAVC GQVTTGKNFG VISCRSCAAF FRRAPTWSRR FPECVKASCA IFENGKFKCK
KCRLKRCQEV GMDVKKIQQN RDLISTSNMF QKRVTLIFGP AHSMSTFLGR PSFLLHCEPE
LASHSKTIID VSYLVDVARK IFEKDATISH KSSNYYNSLE LLTLALDAFR PKDIDKKLTR
LTKIGKNESL LMWEQSFLRA AEWFSNLPSF MKLEDWMKLD ILKSSWLAWT RLEKRCEAAD
YQKSKILENG VFMCGNGSCL AIAEYEVDLS WCTNYTAEQL KYYLSPDSEG QKCIEDLIEL
SPSSTEVNFM ILQLTLHHAG KKSQGRLLEA TENIIEAQAN HLHSYYVEKV KMPNYSARLA
KMMKINRGIA GEMRCRREKN QIARVFDIMK VEFSDPEMFE LT
