NHR98_CAEEL
ID NHR98_CAEEL Reviewed; 433 AA.
AC Q966I0;
DT 15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Nuclear hormone receptor family member nhr-98;
GN Name=nhr-98; ORFNames=M02H5.6;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; FO080236; CCD62239.1; -; Genomic_DNA.
DR AlphaFoldDB; Q966I0; -.
DR STRING; 6239.M02H5.6; -.
DR EPD; Q966I0; -.
DR PaxDb; Q966I0; -.
DR PRIDE; Q966I0; -.
DR UCSC; M02H5.6; c. elegans.
DR WormBase; M02H5.6; CE35342; WBGene00003688; nhr-98.
DR eggNOG; KOG3575; Eukaryota.
DR HOGENOM; CLU_007368_7_1_1; -.
DR InParanoid; Q966I0; -.
DR PhylomeDB; Q966I0; -.
DR PRO; PR:Q966I0; -.
DR Proteomes; UP000001940; Chromosome V.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..433
FT /note="Nuclear hormone receptor family member nhr-98"
FT /id="PRO_0000053802"
FT DOMAIN 177..433
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 41..116
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 44..64
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 80..104
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 433 AA; 49752 MW; 31494E1A18A91CBA CRC64;
MSAAARTFIS IHIGVCFDEM DSPGSSAPSP PDLTIIPKIS SKKCQICENP AHGKHFGAVT
CRACAAFFRR FGISNNFKPC KTENKCSFRK NGYFSCKKCR MQRCLQFGMT IDNFQFDREP
FNPLKMNVGI PQTVDTFSGR PSLILFSAPS GSSGPKRYID VQFLVDRAVE VLLNGSETPY
QVSNVLQKLA IGLQNIRGPQ QKVSQIVTKI GKEGIFKLWE EEMLRMAKWL TYFDDFQRLP
HSVQIEILNG VWFLFGRLEN IASTALARKR KLCKDDMVMT CVNKNVLICD LRTLEIDLSW
CSKYTFQQLK FFDQYDDLRQ LDILINAMLD LEPTHEELSY MICQLCFHQV GKKLQGNILK
TVEKLQEVLS NNLHDYYVNQ MNQPKYSKRI ARMMKINNTV EQCLYRDRVK ADLMKVFEVF
HVECSHPGIF LNA