NHR9_CAEEL
ID NHR9_CAEEL Reviewed; 332 AA.
AC Q23489;
DT 01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 139.
DE RecName: Full=Nuclear hormone receptor family member nhr-9;
GN Name=nhr-9; ORFNames=ZK418.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Orphan nuclear receptor.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407}.
CC -!- SIMILARITY: Belongs to the nuclear hormone receptor family.
CC {ECO:0000305}.
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DR EMBL; FO080150; CCD61620.1; -; Genomic_DNA.
DR PIR; T27857; T27857.
DR RefSeq; NP_498550.1; NM_066149.1.
DR AlphaFoldDB; Q23489; -.
DR SMR; Q23489; -.
DR BioGRID; 56214; 3.
DR STRING; 6239.ZK418.1; -.
DR PaxDb; Q23489; -.
DR EnsemblMetazoa; ZK418.1.1; ZK418.1.1; WBGene00003608.
DR GeneID; 191718; -.
DR KEGG; cel:CELE_ZK418.1; -.
DR UCSC; ZK418.1; c. elegans.
DR CTD; 191718; -.
DR WormBase; ZK418.1; CE00731; WBGene00003608; nhr-9.
DR eggNOG; ENOG502TG42; Eukaryota.
DR GeneTree; ENSGT00970000195839; -.
DR HOGENOM; CLU_007368_3_0_1; -.
DR InParanoid; Q23489; -.
DR OMA; FMEQLTT; -.
DR OrthoDB; 1177755at2759; -.
DR PhylomeDB; Q23489; -.
DR PRO; PR:Q23489; -.
DR Proteomes; UP000001940; Chromosome III.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR Gene3D; 1.10.565.10; -; 1.
DR Gene3D; 3.30.50.10; -; 1.
DR InterPro; IPR035500; NHR-like_dom_sf.
DR InterPro; IPR000536; Nucl_hrmn_rcpt_lig-bd.
DR InterPro; IPR001628; Znf_hrmn_rcpt.
DR InterPro; IPR013088; Znf_NHR/GATA.
DR Pfam; PF00104; Hormone_recep; 1.
DR Pfam; PF00105; zf-C4; 1.
DR PRINTS; PR00047; STROIDFINGER.
DR SMART; SM00430; HOLI; 1.
DR SMART; SM00399; ZnF_C4; 1.
DR SUPFAM; SSF48508; SSF48508; 1.
DR PROSITE; PS51843; NR_LBD; 1.
DR PROSITE; PS00031; NUCLEAR_REC_DBD_1; 1.
DR PROSITE; PS51030; NUCLEAR_REC_DBD_2; 1.
PE 3: Inferred from homology;
KW DNA-binding; Metal-binding; Nucleus; Receptor; Reference proteome;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..332
FT /note="Nuclear hormone receptor family member nhr-9"
FT /id="PRO_0000053762"
FT DOMAIN 101..332
FT /note="NR LBD"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01189"
FT DNA_BIND 11..85
FT /note="Nuclear receptor"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 14..34
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
FT ZN_FING 50..73
FT /note="NR C4-type"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00407"
SQ SEQUENCE 332 AA; 38248 MW; B0239A3AE6B6E594 CRC64;
MITQIGSTSS ERRCAICSKL GNSYNYGVLS CNACKMFFRR ATLGKSEKFC INNDNCDTSN
LILTCRQCRY NKCLKMGMRI VTNQYDSLDD IIKVLAKWNL DRSNKLMNFQ CFEDPTLDQV
IQKHPVFTKK PSNLSFSKSE WGFMEQLTTV EFMSKFEFTR HLFSEDFRIV LKSSCFKIAS
FIKAVRSYSM KKEDIRYPDG ELIVPMELVP FCTSEFLARV QCRLIGRIIE LKLKEEEFLL
LIAIFVCDPT ANNLTARGRE ILSFHQNVYN DALLQLCLRN EGSCGPARFN DLLSVCHVVN
KHVEDIGQLC FMFSFHPPTT KYKRLCAELL GA
