ID   NIFE_KLEPN              Reviewed;         457 AA.
AC   P08737;
DT   01-AUG-1988, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1989, sequence version 2.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE;
OS   Klebsiella pneumoniae.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Klebsiella/Raoultella group; Klebsiella.
OX   NCBI_TaxID=573;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3062178; DOI=10.1016/0022-2836(88)90205-7;
RA   Arnold W., Rump A., Klipp W., Priefer U.B., Puehler A.;
RT   "Nucleotide sequence of a 24,206-base-pair DNA fragment carrying the entire
RT   nitrogen fixation gene cluster of Klebsiella pneumoniae.";
RL   J. Mol. Biol. 203:715-738(1988).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3290850; DOI=10.1093/nar/16.11.5215;
RA   Setterquist R.A., Brigle K.E., Beynon J., Cannon M., Ally A., Cannon F.,
RA   Dean D.R.;
RT   "Nucleotide sequence of the nifE and nifN genes from Klebsiella
RT   pneumoniae.";
RL   Nucleic Acids Res. 16:5215-5215(1988).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; X13303; CAA31671.1; -; Genomic_DNA.
DR   EMBL; X07294; CAA30272.1; -; Genomic_DNA.
DR   PIR; S01839; S01839.
DR   AlphaFoldDB; P08737; -.
DR   SMR; P08737; -.
DR   PRIDE; P08737; -.
DR   UniPathway; UPA00782; -.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation.
FT   CHAIN           1..457
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153115"
FT   CONFLICT        166
FT                   /note="P -> L (in Ref. 2; CAA30272)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        333
FT                   /note="G -> A (in Ref. 2; CAA30272)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   457 AA;  50154 MW;  C7156E0CACE65309 CRC64;
     MKGNEILALL DEPACEHNHK QKSGCSAPKP GATAAGCAFD GAQITLLPIA DVAHLVHGPI
     GCAGSSWDNR GSASSGPTLN RLGFTTDLNE QDVIMGRGER RLFHAVRHIV TRYHPAAVFI
     YNTCVPAMEG DDLEAVCQAA QTATGVPVIA IDAAGFYGSK NLGNRPAGDV MVKRVIGQRE
     PAPWPESTLF APEQRHDIGL IGEFNIAGEF WHIQPLLDEL GIRVLGSLSG DGRFAEIQTM
     HRAQANMLVC SRALINVARA LEQRYGTPWF EGSFYGIRAT SDALRQLAAL LGDDDLRQRT
     EALIAREEQA AELALQPWRE QLRGRKALLY TGGVKSWSVV SALQDLGMTV VATGTRKSTE
     EDKQRIRELM GEEAVMLEEG NARTLLDVVY RYQADLMIAG GRNMYTAYKA RLPFLDINQE
     REHAFAGYQG IVTLARQLCQ TINSPIWPQT HSRAPWR