ID   NIFE_METMP              Reviewed;         480 AA.
AC   P0CW55; P71528;
DT   03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT   03-MAY-2011, sequence version 1.
DT   03-AUG-2022, entry version 46.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=MMP0858;
OS   Methanococcus maripaludis (strain S2 / LL).
OC   Archaea; Euryarchaeota; Methanomada group; Methanococci; Methanococcales;
OC   Methanococcaceae; Methanococcus.
OX   NCBI_TaxID=267377;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S2 / LL;
RX   PubMed=15466049; DOI=10.1128/jb.186.20.6956-6969.2004;
RA   Hendrickson E.L., Kaul R., Zhou Y., Bovee D., Chapman P., Chung J.,
RA   Conway de Macario E., Dodsworth J.A., Gillett W., Graham D.E., Hackett M.,
RA   Haydock A.K., Kang A., Land M.L., Levy R., Lie T.J., Major T.A.,
RA   Moore B.C., Porat I., Palmeiri A., Rouse G., Saenphimmachak C., Soell D.,
RA   Van Dien S., Wang T., Whitman W.B., Xia Q., Zhang Y., Larimer F.W.,
RA   Olson M.V., Leigh J.A.;
RT   "Complete genome sequence of the genetically tractable hydrogenotrophic
RT   methanogen Methanococcus maripaludis.";
RL   J. Bacteriol. 186:6956-6969(2004).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor). {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; BX950229; CAF30414.1; -; Genomic_DNA.
DR   RefSeq; WP_011170802.1; NC_005791.1.
DR   AlphaFoldDB; P0CW55; -.
DR   SMR; P0CW55; -.
DR   STRING; 267377.MMP0858; -.
DR   EnsemblBacteria; CAF30414; CAF30414; MMP0858.
DR   GeneID; 2762315; -.
DR   KEGG; mmp:MMP0858; -.
DR   PATRIC; fig|267377.15.peg.883; -.
DR   eggNOG; arCOG00598; Archaea.
DR   HOGENOM; CLU_025876_1_1_2; -.
DR   OMA; SWDNRGT; -.
DR   OrthoDB; 10827at2157; -.
DR   BioCyc; MMAR267377:MMP_RS04465-MON; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000000590; Chromosome.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Reference proteome.
FT   CHAIN           1..480
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000408204"
SQ   SEQUENCE   480 AA;  53289 MW;  7763F7125E76B948 CRC64;
     MVLNLDTENR KMQDGNNDDD FDLEVKIPNS IFEKLKSIEA LKARESQMCV SGKDDSIPTC
     DKNSTPGMIT QRSCVYGGAR VVLMPITDAV HLVHGPIGCA ACTWDIRGSK STGDKLYKNG
     FSTDLQEKDI VFGGEKKLYE SILEVNKLYH PGAIFVYSTC VVGLIGDDLK AVCRQAQEAT
     GCRVIPVQSE GFKSFNKTAG HKLACDAMLD YVIGTEEPEE EHPYSINIIG EFNVAGDLWG
     IIPLYEKMGV KVHTAITGDS TVAKVASAHR SKLNIVQCQK SSNYLAAQME KKYGIPSIKV
     NFFGLDETTK SLRAVAEFFG DEEMIKRTEE LIKSEIKNLR DEISEYKKDL SGRTVAIYSG
     AHKSWALVSA FGELDMEIIM SGTQNGKPED YQQIRDHVCE GTLIVDDASS MELVQLLKEY
     KPDILISGAK EKYLSLKSGI PHCDFNHDRI TAFSGYQGFI NFARVVHTAV MTPIWRLSRK