ID   NIFE_METTM              Reviewed;         480 AA.
AC   P95297; D9PU62;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   30-NOV-2010, sequence version 2.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=MTBMA_c01510;
OS   Methanothermobacter marburgensis (strain ATCC BAA-927 / DSM 2133 / JCM
OS   14651 / NBRC 100331 / OCM 82 / Marburg) (Methanobacterium
OS   thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=79929;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RA   Hochheimer A.;
RL   Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-927 / DSM 2133 / JCM 14651 / NBRC 100331 / OCM 82 /
RC   Marburg;
RX   PubMed=20802048; DOI=10.1128/jb.00844-10;
RA   Liesegang H., Kaster A.K., Wiezer A., Goenrich M., Wollherr A., Seedorf H.,
RA   Gottschalk G., Thauer R.K.;
RT   "Complete genome sequence of Methanothermobacter marburgensis, a
RT   methanoarchaeon model organism.";
RL   J. Bacteriol. 192:5850-5851(2010).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; X87971; CAA61221.1; -; Genomic_DNA.
DR   EMBL; CP001710; ADL57760.1; -; Genomic_DNA.
DR   RefSeq; WP_013294988.1; NC_014408.1.
DR   AlphaFoldDB; P95297; -.
DR   SMR; P95297; -.
DR   STRING; 79929.MTBMA_c01510; -.
DR   PRIDE; P95297; -.
DR   EnsemblBacteria; ADL57760; ADL57760; MTBMA_c01510.
DR   GeneID; 9703856; -.
DR   KEGG; mmg:MTBMA_c01510; -.
DR   PATRIC; fig|79929.8.peg.147; -.
DR   HOGENOM; CLU_025876_1_1_2; -.
DR   OMA; SWDNRGT; -.
DR   OrthoDB; 10827at2157; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000000345; Chromosome.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation.
FT   CHAIN           1..480
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153119"
FT   CONFLICT        47..54
FT                   /note="SGGGPRCN -> RGEGPDLD (in Ref. 1; CAA61221)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   480 AA;  52842 MW;  6DC9532EC22A14D9 CRC64;
     MNHSTGNCSS KENFSADTTA DLKVEEVPEA VINTLSPRRE HFTRSCSGGG PRCNRESLPG
     MVTQRSCVYG GARVVLMPIT DAAHLVHGPV GCAACTWDIR GSRSSKSELY RMGFSTGLEE
     KDVVFGGEDK LLECILEINE IHSPSAIFVY STCVSGVIGD DIAAVCRTAE NKTGKWVIQV
     QSEGFRSFNK SLGHQLACDV ILRHIIGRGD AEVRENSVNL VGEFNVAGDL WEIKGLLEKM
     GIHVVSSITG DSTVAEISEA HTAQLNIVQC SKSSGYIAEE MKRKYGIPYI NVNFFGIKET
     MDSLLSISDF FDLNAEERIS SMAEKTHEMI RGYRRALEGK KVAIYVGGNK AWSLIRAFRD
     LGMEVIMSGT QNGLPEDYLK IMEKSGRELI LFDDANPVEL SELLRKYRPD LVVSGAKEKY
     LSYKLGIPFC EFNHDRIKPF SGFGGFLNFA EEVKRTLESP IWTLASKKRL SGPGGMSGEA