ID   NIFE_NOSS1              Reviewed;         480 AA.
AC   Q44144;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=all1438;
OS   Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Nostoc.
OX   NCBI_TaxID=103690;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Buikema W.J., Scappino L.A., Haselkorn R.;
RL   Submitted (JAN-1996) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 7120 / SAG 25.82 / UTEX 2576;
RX   PubMed=11759840; DOI=10.1093/dnares/8.5.205;
RA   Kaneko T., Nakamura Y., Wolk C.P., Kuritz T., Sasamoto S., Watanabe A.,
RA   Iriguchi M., Ishikawa A., Kawashima K., Kimura T., Kishida Y., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takazawa M., Yamada M., Yasuda M., Tabata S.;
RT   "Complete genomic sequence of the filamentous nitrogen-fixing
RT   cyanobacterium Anabaena sp. strain PCC 7120.";
RL   DNA Res. 8:205-213(2001).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; U47055; AAA87947.1; -; Genomic_DNA.
DR   EMBL; BA000019; BAB73395.1; -; Genomic_DNA.
DR   PIR; AC1986; AC1986.
DR   RefSeq; WP_010995610.1; NC_003272.1.
DR   AlphaFoldDB; Q44144; -.
DR   SMR; Q44144; -.
DR   STRING; 103690.17130785; -.
DR   PRIDE; Q44144; -.
DR   EnsemblBacteria; BAB73395; BAB73395; BAB73395.
DR   KEGG; ana:all1438; -.
DR   eggNOG; COG2710; Bacteria.
DR   OMA; SWDNRGT; -.
DR   OrthoDB; 363662at2; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000002483; Chromosome.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Reference proteome.
FT   CHAIN           1..480
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153111"
FT   REGION          12..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        16..30
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   480 AA;  52805 MW;  F4F1D1BC968665DF CRC64;
     MKNTQGKINE LLNESGCEHN QHKHGEKKNK SCSQQAQPGA AQGGCAFDGA MISLVPIVDA
     AHLVHGPIAC AGNSWGSRGS LSSGPQLYKM GFTTDMSEND VIFGGEKKLY KAILEIHKRY
     NPSAVFVYAT CVTALIGDDI DAVCKTAAEK IGTPVIPVIA PGFIGSKNLG NRFGGESLLD
     YVVGTAEPEY TTPYDINLIG EYNIAGEMWG VLPLLEKLGI RVLSKITGDA RFEEIRYAHR
     AKLNVMICSR ALLNMARKME ENYGIPYIEE SFYGIDDMNR CLRNIAAKLG DPDLQARTEK
     LIAEETAALD LALAPYRARL KGKRVVLYTG GVKSWSIISA AKDLGIEVVA TSTRKSTEED
     KAKIKRLLGA DGIMLEKGNA KELLQLVKDT QADMLIAGGR NQYTALKARI PFLDINQERH
     HPYAGYVGMI EMARELYEAL YSPIWEQIRK PAPWDEDMGI LAHEYTSNHD HILASIEELI