ID   NIFE_RHIME              Reviewed;         476 AA.
AC   Q92ZL2;
DT   23-JAN-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2001, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=RA0452; ORFNames=SMa0830;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OG   Plasmid pSymA (megaplasmid 1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481432; DOI=10.1073/pnas.161294798;
RA   Barnett M.J., Fisher R.F., Jones T., Komp C., Abola A.P., Barloy-Hubler F.,
RA   Bowser L., Capela D., Galibert F., Gouzy J., Gurjal M., Hong A., Huizar L.,
RA   Hyman R.W., Kahn D., Kahn M.L., Kalman S., Keating D.H., Palm C.,
RA   Peck M.C., Surzycki R., Wells D.H., Yeh K.-C., Davis R.W., Federspiel N.A.,
RA   Long S.R.;
RT   "Nucleotide sequence and predicted functions of the entire Sinorhizobium
RT   meliloti pSymA megaplasmid.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9883-9888(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; AE006469; AAK65110.1; -; Genomic_DNA.
DR   PIR; D95318; D95318.
DR   RefSeq; NP_435698.1; NC_003037.1.
DR   RefSeq; WP_010967435.1; NC_003037.1.
DR   AlphaFoldDB; Q92ZL2; -.
DR   SMR; Q92ZL2; -.
DR   EnsemblBacteria; AAK65110; AAK65110; SMa0830.
DR   GeneID; 61599262; -.
DR   KEGG; sme:SMa0830; -.
DR   PATRIC; fig|266834.11.peg.465; -.
DR   HOGENOM; CLU_025876_1_1_5; -.
DR   OMA; SWDNRGT; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000001976; Plasmid pSymA.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Plasmid; Reference proteome.
FT   CHAIN           1..476
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153121"
SQ   SEQUENCE   476 AA;  52359 MW;  83ECE94B4B14C713 CRC64;
     MPSLSAKNQA FFNEPACERN RSKDFKVRKK GCSQPPMPGA AAGGCAFDGA KVALQPITNV
     AHLIHAPLAC EGNSWDNRGT ASSSHMLWRT SFTTDVTEFD VVMGHSERKL FKAIREINEA
     YAPAAVFVYA TCVTALIGDD IDAVCRRAAE KFGLPVVPVN APGFVGSKNL GNKLAGEALL
     DHVIGTVEPD DARSSDINIL GEFNLSGEFW QVRPLLDKLG VRVRACIPGD SRYLDIATAH
     RARAAMMVCS TALINLARKM LERWDIPFFE GSFYGITDTS EALRQIAGLL VKQGAGPDLI
     SRTEALIVEE EARAWRRLEV YRPRLQGKRV LLNTGGVKSW SVAHALMEIG LEIVGTSIKK
     STDNDKERLK QMLTNDSRMS GATTPRELYS ALSDHKADIM LSGGRTQFIA LKAKMPWLDI
     NQERQHSYAG YHGVVELARQ IDLSIHNPIW AQVREAAPWE MAPARGEEMS EEEALL