ID   NIFE_RIPO1              Reviewed;         470 AA.
AC   O07355; B7JWY5;
DT   15-JUL-1999, integrated into UniProtKB/Swiss-Prot.
DT   14-APR-2009, sequence version 2.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Nitrogenase iron-molybdenum cofactor biosynthesis protein NifE;
GN   Name=nifE; OrderedLocusNames=PCC8801_1788;
OS   Rippkaea orientalis (strain PCC 8801) (Cyanothece sp. (strain PCC 8801)).
OC   Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC   Aphanothecaceae; Rippkaea; Rippkaea orientalis.
OX   NCBI_TaxID=41431;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=10217509; DOI=10.1099/13500872-145-3-743;
RA   Huang T.-C., Lin R.-F., Chu M.-K., Chen H.-M.;
RT   "Organization and expression of nitrogen-fixation genes in the aerobic
RT   nitrogen-fixing unicellular cyanobacterium Synechococcus sp. strain RF-1.";
RL   Microbiology 145:743-753(1999).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 8801;
RX   PubMed=21972240; DOI=10.1128/mbio.00214-11;
RA   Bandyopadhyay A., Elvitigala T., Welsh E., Stockel J., Liberton M., Min H.,
RA   Sherman L.A., Pakrasi H.B.;
RT   "Novel metabolic attributes of the genus Cyanothece, comprising a group of
RT   unicellular nitrogen-fixing Cyanobacteria.";
RL   MBio 2:E214-E214(2011).
CC   -!- FUNCTION: This protein may play a role in the biosynthesis of the
CC       prosthetic group of nitrogenase (FeMo cofactor).
CC   -!- PATHWAY: Cofactor biosynthesis; Fe-Mo cofactor biosynthesis.
CC   -!- SIMILARITY: Belongs to the NifD/NifK/NifE/NifN family. {ECO:0000305}.
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DR   EMBL; AF003700; AAC35194.1; -; Genomic_DNA.
DR   EMBL; CP001287; ACK65834.1; -; Genomic_DNA.
DR   RefSeq; WP_012595107.1; NC_011726.1.
DR   AlphaFoldDB; O07355; -.
DR   SMR; O07355; -.
DR   STRING; 41431.PCC8801_1788; -.
DR   PRIDE; O07355; -.
DR   EnsemblBacteria; ACK65834; ACK65834; PCC8801_1788.
DR   KEGG; cyp:PCC8801_1788; -.
DR   eggNOG; COG2710; Bacteria.
DR   HOGENOM; CLU_025876_1_1_3; -.
DR   OMA; SWDNRGT; -.
DR   OrthoDB; 363662at2; -.
DR   UniPathway; UPA00782; -.
DR   Proteomes; UP000008204; Chromosome.
DR   GO; GO:0016163; F:nitrogenase activity; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   GO; GO:0065003; P:protein-containing complex assembly; IEA:InterPro.
DR   InterPro; IPR000510; Nase/OxRdtase_comp1.
DR   InterPro; IPR000318; Nase_comp1_CS.
DR   InterPro; IPR005973; NifE.
DR   Pfam; PF00148; Oxidored_nitro; 1.
DR   TIGRFAMs; TIGR01283; nifE; 1.
DR   PROSITE; PS00699; NITROGENASE_1_1; 1.
DR   PROSITE; PS00090; NITROGENASE_1_2; 1.
PE   3: Inferred from homology;
KW   Nitrogen fixation; Reference proteome.
FT   CHAIN           1..470
FT                   /note="Nitrogenase iron-molybdenum cofactor biosynthesis
FT                   protein NifE"
FT                   /id="PRO_0000153124"
FT   REGION          11..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        29..42
FT                   /note="NKSCTQQAQPGSAQ -> TNLVPNRLNLAQHK (in Ref. 1;
FT                   AAC35194)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        234
FT                   /note="Missing (in Ref. 1; AAC35194)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   470 AA;  51837 MW;  C699240A46FBA7CB CRC64;
     MKLTKGKINE LLTQPGCEHN HNKEGQGKNK SCTQQAQPGS AQGGCAFDGA SIALVPITDA
     AHLVHGSIAC SGNSWNSRGS LSSGPMTYKM GFTTDLSEND VIFGGEKKLY QAIAQLVKRY
     HPAAVFVYST CVTALIGDDL DAVCKAATKK YETPIIPVHA PGFVGSKNLG NRLGGEALLD
     HVVGTREPEF TTDFDINLIG EYNVAGEMWG VLPLFEKLGI RVLAKITGDA RYEEVCYAHR
     AKLNLMICSK ALINMATAMQ ERYGIPYIEE SFYGIADMNR CLRNIAEYFG DAALKERVEQ
     LIEEETTKLD LALAPYRERL KGKRVVLYTG GVKSWSVVSA AQDLGMEVVA TSTKKSTEED
     KAKIRELLGK DGIMLEKGSP TELLRVVEQT KADLLVAGGR NQYTALKARI PFLDINQERH
     HPYAGYVGMI EMARELDEAV HSPIWRLVRQ PSPWDIWQQE HESLLNLEAE