ID   NIFP_AZOCH              Reviewed;         269 AA.
AC   P23145;
DT   01-NOV-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1991, sequence version 1.
DT   03-AUG-2022, entry version 73.
DE   RecName: Full=Probable serine acetyltransferase;
DE            Short=SAT;
DE            EC=2.3.1.30;
GN   Name=nifP;
OS   Azotobacter chroococcum mcd 1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Azotobacter.
OX   NCBI_TaxID=355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1885524; DOI=10.1128/jb.173.17.5457-5469.1991;
RA   Evans D.J., Jones R., Woodley P.R., Wilborn J.R., Robson R.L.;
RT   "Nucleotide sequence and genetic analysis of the Azotobacter chroococcum
RT   nifUSVWZM gene cluster, including a new gene (nifP) which encodes a serine
RT   acetyltransferase.";
RL   J. Bacteriol. 173:5457-5469(1991).
CC   -!- FUNCTION: Probable serine acetyltransferase required for optimizing the
CC       expression of nitrogenase activity. May be required to boost rates of
CC       synthesis or intracellular concentrations of cysteine or methionine.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=acetyl-CoA + L-serine = CoA + O-acetyl-L-serine;
CC         Xref=Rhea:RHEA:24560, ChEBI:CHEBI:33384, ChEBI:CHEBI:57287,
CC         ChEBI:CHEBI:57288, ChEBI:CHEBI:58340; EC=2.3.1.30;
CC   -!- SIMILARITY: Belongs to the transferase hexapeptide repeat family.
CC       {ECO:0000305}.
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DR   EMBL; M60090; AAA22162.1; -; Genomic_DNA.
DR   PIR; D43706; D43706.
DR   AlphaFoldDB; P23145; -.
DR   SMR; P23145; -.
DR   PRIDE; P23145; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR   GO; GO:0009001; F:serine O-acetyltransferase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006535; P:cysteine biosynthetic process from serine; IEA:InterPro.
DR   GO; GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW.
DR   CDD; cd03354; LbH_SAT; 1.
DR   Gene3D; 1.10.3130.10; -; 1.
DR   InterPro; IPR001451; Hexapep.
DR   InterPro; IPR018357; Hexapep_transf_CS.
DR   InterPro; IPR045304; LbH_SAT.
DR   InterPro; IPR042122; Ser_AcTrfase_N_sf.
DR   InterPro; IPR005881; Ser_O-AcTrfase.
DR   InterPro; IPR011004; Trimer_LpxA-like_sf.
DR   Pfam; PF00132; Hexapep; 2.
DR   SUPFAM; SSF51161; SSF51161; 1.
DR   TIGRFAMs; TIGR01172; cysE; 1.
DR   PROSITE; PS00101; HEXAPEP_TRANSFERASES; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Amino-acid biosynthesis; Cysteine biosynthesis;
KW   Nitrogen fixation; Repeat; Transferase.
FT   CHAIN           1..269
FT                   /note="Probable serine acetyltransferase"
FT                   /id="PRO_0000068689"
FT   REGION          242..269
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        253..269
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   269 AA;  28578 MW;  E0BBCC982E66FDBB CRC64;
     MSLLAQWRED IRCVFERDPA ARTTFEVLTT YPGVHAIMLY RLAHRLWRPN ALPRPAAVVR
     ARLVSNVDIH PGAVIGARFF IDHGACVVIG ETAEIGRDVT LYHGVTLGGT TGAKGKRHPT
     LGDVVLVGAG AKILGPITIG ANARVGANSV VVQDVPEGCT VVGIPGKVVK LREAGQLNPY
     GIDLDHHLIP DPVGKAIACL LERIDSLEKR VEAGGLVAAA ASSTFYEGCN PDNSICETNL
     RRSAPWSSGR PRRPAHAGDR VSGRAKGSD