ID   NIFSL_ASFP4             Reviewed;         387 AA.
AC   P0C9C9;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 35.
DE   RecName: Full=NifS-like protein;
GN   OrderedLocusNames=Pret-136;
OS   African swine fever virus (isolate Tick/South Africa/Pretoriuskop Pr4/1996)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561443;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=pyridoxal 5'-phosphate; Xref=ChEBI:CHEBI:597326;
CC         Evidence={ECO:0000250|UniProtKB:P0A6B9};
CC   -!- SUBCELLULAR LOCATION: Virion {ECO:0000250|UniProtKB:Q65192}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the class-V pyridoxal-phosphate-dependent
CC       aminotransferase family. NifS/IscS subfamily. {ECO:0000305}.
CC   -!- CAUTION: Although related to the NifS/IscS subfamily, lacks the
CC       conserved active site, suggesting it has no transferase activity.
CC       {ECO:0000305}.
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DR   EMBL; AY261363; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; P0C9C9; -.
DR   Proteomes; UP000000859; Genome.
DR   GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR   Gene3D; 3.40.640.10; -; 1.
DR   Gene3D; 3.90.1150.10; -; 1.
DR   InterPro; IPR000192; Aminotrans_V_dom.
DR   InterPro; IPR015424; PyrdxlP-dep_Trfase.
DR   InterPro; IPR015421; PyrdxlP-dep_Trfase_major.
DR   InterPro; IPR015422; PyrdxlP-dep_Trfase_small.
DR   Pfam; PF00266; Aminotran_5; 1.
DR   SUPFAM; SSF53383; SSF53383; 1.
PE   3: Inferred from homology;
KW   Late protein; Virion.
FT   CHAIN           1..387
FT                   /note="NifS-like protein"
FT                   /id="PRO_0000373144"
FT   BINDING         58..59
FT                   /ligand="pyridoxal 5'-phosphate"
FT                   /ligand_id="ChEBI:CHEBI:597326"
FT                   /evidence="ECO:0000250|UniProtKB:P0A6B9"
FT   BINDING         184..186
FT                   /ligand="pyridoxal 5'-phosphate"
FT                   /ligand_id="ChEBI:CHEBI:597326"
FT                   /evidence="ECO:0000250|UniProtKB:P0A6B9"
SQ   SEQUENCE   387 AA;  43008 MW;  D3540416D8A878AA CRC64;
     MASILTLDGL YAEVPKFLPE ALREGCAGKN PLSFYIQQIL NLMGCDGNEY HVLFTSSSEE
     ANTHMIMAAV RRHLLRTQQR PHVIIGAGEP PSITECVKAL AQEKRCVYTI IPLKNFEIDP
     VAVYDAIQSN TCLACISGTN AVVKTFNKLQ DISKVLRGIP LHSEVSDLVY QGCIKQNPPA
     DSFSINSLYG FLGVGILGMK KKVMQGLGPL IFGGGLRGGS PNIPGIHAMY RTLTQQRPSI
     KKINTIHKLF MKTLKKHQHV YLPIGGVSAE DMSTKDMSTK DIPSTDMLVG PKGLPGYILF
     SVGHRAEELQ KKIFTKFNIK IGRIVDLQEI LFRIKIPQKY WETLLFIQLR DNLTKEDIKR
     VMVVLMHLDT ITPRGSLPPP SYSSSFS