ID   NIKE_RHORT              Reviewed;         277 AA.
AC   Q2RS22;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 104.
DE   RecName: Full=Nickel import ATP-binding protein NikE {ECO:0000255|HAMAP-Rule:MF_01712};
DE            EC=7.2.2.11 {ECO:0000255|HAMAP-Rule:MF_01712};
GN   Name=nikE {ECO:0000255|HAMAP-Rule:MF_01712}; OrderedLocusNames=Rru_A2273;
OS   Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 /
OS   NCIMB 8255 / S1).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodospirillales;
OC   Rhodospirillaceae; Rhodospirillum.
OX   NCBI_TaxID=269796;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1;
RX   PubMed=21886856; DOI=10.4056/sigs.1804360;
RA   Munk A.C., Copeland A., Lucas S., Lapidus A., Del Rio T.G., Barry K.,
RA   Detter J.C., Hammon N., Israni S., Pitluck S., Brettin T., Bruce D.,
RA   Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M., Kyrpides N.C.,
RA   Mavromatis K., Richardson P., Rohde M., Goeker M., Klenk H.P., Zhang Y.,
RA   Roberts G.P., Reslewic S., Schwartz D.C.;
RT   "Complete genome sequence of Rhodospirillum rubrum type strain (S1).";
RL   Stand. Genomic Sci. 4:293-302(2011).
CC   -!- FUNCTION: Part of the ABC transporter complex NikABCDE involved in
CC       nickel import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01712}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate;
CC         Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786,
CC         ChEBI:CHEBI:456216; EC=7.2.2.11; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01712};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (NikD and
CC       NikE), two transmembrane proteins (NikB and NikC) and a solute-binding
CC       protein (NikA). {ECO:0000255|HAMAP-Rule:MF_01712}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01712}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01712}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Nickel importer
CC       (TC 3.A.1.5.3) family. {ECO:0000255|HAMAP-Rule:MF_01712}.
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DR   EMBL; CP000230; ABC23073.1; -; Genomic_DNA.
DR   RefSeq; WP_011389928.1; NC_007643.1.
DR   RefSeq; YP_427360.1; NC_007643.1.
DR   AlphaFoldDB; Q2RS22; -.
DR   SMR; Q2RS22; -.
DR   STRING; 269796.Rru_A2273; -.
DR   EnsemblBacteria; ABC23073; ABC23073; Rru_A2273.
DR   KEGG; rru:Rru_A2273; -.
DR   PATRIC; fig|269796.9.peg.2371; -.
DR   eggNOG; COG1124; Bacteria.
DR   HOGENOM; CLU_000604_1_23_5; -.
DR   OMA; LVERFCH; -.
DR   OrthoDB; 1303270at2; -.
DR   PhylomeDB; Q2RS22; -.
DR   Proteomes; UP000001929; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015413; F:ABC-type nickel transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR014137; Nickel_NikE.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02769; nickel_nikE; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51248; NIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Nickel; Nickel transport; Nucleotide-binding; Reference proteome;
KW   Translocase; Transport.
FT   CHAIN           1..277
FT                   /note="Nickel import ATP-binding protein NikE"
FT                   /id="PRO_0000274122"
FT   DOMAIN          14..253
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01712"
FT   BINDING         46..53
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01712"
SQ   SEQUENCE   277 AA;  30050 MW;  F9A700B1DB1CA95B CRC64;
     MSPLLTARAA SKSYRTVSLV GRSPAKTVLS EATVTLSEGE TVALLGRSGS GKSTLARLLL
     GLEKPDHGTI AFRGRPLGGF SRAEWRAFRG AVQMVFQDSL GAVNPRHRVG RIIGEPLRHL
     TTLDDAGRAA RRDALLRQVG LTPEDADKLP QQMSGGQLQR VCIARALAPG PRLLVLDEAV
     SNLDLMLQIQ MIDLLKDLQR QTGMAYLFVT HDLRLVERFC QRVIVLDEGK IVEEAPVTGA
     QRFEHPASRA LQRAILPARP AAASVGDDEG GRRSATR