ID   NIKE_SHIBS              Reviewed;         268 AA.
AC   Q31VE6;
DT   23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT   06-DEC-2005, sequence version 1.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Nickel import ATP-binding protein NikE {ECO:0000255|HAMAP-Rule:MF_01712};
DE            EC=7.2.2.11 {ECO:0000255|HAMAP-Rule:MF_01712};
GN   Name=nikE {ECO:0000255|HAMAP-Rule:MF_01712}; OrderedLocusNames=SBO_3477;
OS   Shigella boydii serotype 4 (strain Sb227).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=300268;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Sb227;
RX   PubMed=16275786; DOI=10.1093/nar/gki954;
RA   Yang F., Yang J., Zhang X., Chen L., Jiang Y., Yan Y., Tang X., Wang J.,
RA   Xiong Z., Dong J., Xue Y., Zhu Y., Xu X., Sun L., Chen S., Nie H., Peng J.,
RA   Xu J., Wang Y., Yuan Z., Wen Y., Yao Z., Shen Y., Qiang B., Hou Y., Yu J.,
RA   Jin Q.;
RT   "Genome dynamics and diversity of Shigella species, the etiologic agents of
RT   bacillary dysentery.";
RL   Nucleic Acids Res. 33:6445-6458(2005).
CC   -!- FUNCTION: Part of the ABC transporter complex NikABCDE involved in
CC       nickel import. Responsible for energy coupling to the transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_01712}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + H2O + Ni(2+)(out) = ADP + H(+) + Ni(2+)(in) + phosphate;
CC         Xref=Rhea:RHEA:15557, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:43474, ChEBI:CHEBI:49786,
CC         ChEBI:CHEBI:456216; EC=7.2.2.11; Evidence={ECO:0000255|HAMAP-
CC         Rule:MF_01712};
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (NikD and
CC       NikE), two transmembrane proteins (NikB and NikC) and a solute-binding
CC       protein (NikA). {ECO:0000255|HAMAP-Rule:MF_01712}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01712}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01712}.
CC   -!- SIMILARITY: Belongs to the ABC transporter superfamily. Nickel importer
CC       (TC 3.A.1.5.3) family. {ECO:0000255|HAMAP-Rule:MF_01712}.
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DR   EMBL; CP000036; ABB67962.1; -; Genomic_DNA.
DR   RefSeq; WP_000173706.1; NC_007613.1.
DR   AlphaFoldDB; Q31VE6; -.
DR   SMR; Q31VE6; -.
DR   EnsemblBacteria; ABB67962; ABB67962; SBO_3477.
DR   KEGG; sbo:SBO_3477; -.
DR   HOGENOM; CLU_000604_1_23_6; -.
DR   OMA; LVERFCH; -.
DR   Proteomes; UP000007067; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015413; F:ABC-type nickel transporter activity; IEA:UniProtKB-EC.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016151; F:nickel cation binding; IEA:InterPro.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR   InterPro; IPR017871; ABC_transporter-like_CS.
DR   InterPro; IPR014137; Nickel_NikE.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   Pfam; PF00005; ABC_tran; 1.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR02769; nickel_nikE; 1.
DR   PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR   PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
DR   PROSITE; PS51248; NIKE; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Cell inner membrane; Cell membrane; Ion transport; Membrane;
KW   Nickel; Nickel transport; Nucleotide-binding; Translocase; Transport.
FT   CHAIN           1..268
FT                   /note="Nickel import ATP-binding protein NikE"
FT                   /id="PRO_0000274123"
FT   DOMAIN          4..252
FT                   /note="ABC transporter"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01712"
FT   BINDING         45..52
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01712"
SQ   SEQUENCE   268 AA;  29644 MW;  65D7FB2274AD309B CRC64;
     MTLLNVSGLS HHYAHGGFSG KHQHQAVLNN VSLTLKSGET VALLGRSGCG KSTLARLLVG
     LESPSQGNIS WRGESLAKLN RAQRKAFRRD IQMVFQDSIS AVNPRKTVRE ILREPMRHLL
     SLKKSEQLAR ASEMLKAVDL DDSVLDKRPP QLSGGQLQRV CLARALAVEP KLLILDETVS
     NLDLVLQAGV IRLLKKLQQQ FGTACLFITH DLRLVERFCQ RVMVMDNGQI VETQAVGDKL
     TFSSDAGRVL QNAVLPAFPV RRRATEKV