NIKMN_ARCFU
ID NIKMN_ARCFU Reviewed; 295 AA.
AC O28435;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 27-JUL-2011, sequence version 2.
DT 25-MAY-2022, entry version 88.
DE RecName: Full=Putative fused nickel transport protein NikMN;
GN OrderedLocusNames=AF_1843;
OS Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC
OS 100126 / VC-16).
OC Archaea; Euryarchaeota; Archaeoglobi; Archaeoglobales; Archaeoglobaceae;
OC Archaeoglobus.
OX NCBI_TaxID=224325;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16;
RX PubMed=9389475; DOI=10.1038/37052;
RA Klenk H.-P., Clayton R.A., Tomb J.-F., White O., Nelson K.E., Ketchum K.A.,
RA Dodson R.J., Gwinn M.L., Hickey E.K., Peterson J.D., Richardson D.L.,
RA Kerlavage A.R., Graham D.E., Kyrpides N.C., Fleischmann R.D.,
RA Quackenbush J., Lee N.H., Sutton G.G., Gill S.R., Kirkness E.F.,
RA Dougherty B.A., McKenney K., Adams M.D., Loftus B.J., Peterson S.N.,
RA Reich C.I., McNeil L.K., Badger J.H., Glodek A., Zhou L., Overbeek R.,
RA Gocayne J.D., Weidman J.F., McDonald L.A., Utterback T.R., Cotton M.D.,
RA Spriggs T., Artiach P., Kaine B.P., Sykes S.M., Sadow P.W., D'Andrea K.P.,
RA Bowman C., Fujii C., Garland S.A., Mason T.M., Olsen G.J., Fraser C.M.,
RA Smith H.O., Woese C.R., Venter J.C.;
RT "The complete genome sequence of the hyperthermophilic, sulphate-reducing
RT archaeon Archaeoglobus fulgidus.";
RL Nature 390:364-370(1997).
RN [2]
RP PREDICTION OF FUNCTION.
RC STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX PubMed=16352848; DOI=10.1128/jb.188.1.317-327.2006;
RA Rodionov D.A., Hebbeln P., Gelfand M.S., Eitinger T.;
RT "Comparative and functional genomic analysis of prokaryotic nickel and
RT cobalt uptake transporters: evidence for a novel group of ATP-binding
RT cassette transporters.";
RL J. Bacteriol. 188:317-327(2006).
CC -!- FUNCTION: May be involved in nickel transport.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the CbiM family. NikM subfamily. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB89410.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AE000782; AAB89410.1; ALT_INIT; Genomic_DNA.
DR PIR; B69480; B69480.
DR RefSeq; WP_048064472.1; NC_000917.1.
DR AlphaFoldDB; O28435; -.
DR SMR; O28435; -.
DR STRING; 224325.AF_1843; -.
DR EnsemblBacteria; AAB89410; AAB89410; AF_1843.
DR GeneID; 24795587; -.
DR KEGG; afu:AF_1843; -.
DR eggNOG; arCOG02248; Archaea.
DR HOGENOM; CLU_052508_0_1_2; -.
DR OrthoDB; 73296at2157; -.
DR Proteomes; UP000002199; Chromosome.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015675; P:nickel cation transport; IEA:UniProtKB-KW.
DR InterPro; IPR002751; CbiM/NikMN.
DR InterPro; IPR025937; PDGLE_dom.
DR Pfam; PF01891; CbiM; 1.
DR Pfam; PF13190; PDGLE; 1.
PE 3: Inferred from homology;
KW Cell membrane; Ion transport; Membrane; Nickel; Nickel transport;
KW Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..295
FT /note="Putative fused nickel transport protein NikMN"
FT /id="PRO_0000412172"
FT TRANSMEM 8..28
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 39..59
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 70..90
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 98..118
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 175..195
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 211..231
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 268..288
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 295 AA; 30664 MW; 361208BB2D4DE9AC CRC64;
MHIPDGYLDL SIAGLFYILS IAVLGYSIYR LRGQKLTSLF GIVAAAIFAA QMLNWPIPGG
TSAHFVGGAL AGILLGPYAG ALAMAVVLTI QCLVFADGGI TALGANVWNM AIVNVFVGYY
VYRAIERFNR SAAAFIAGWI GITLAAIFAG IEIGISTSFG YGLKVTLPVM GTWHALLGLV
EGTITAGVVS YIAAARPDVI EQKAAPGKLA LAVIAAMIAV SPLFAYAAEL VGYSEPLENA
AAMLGLEENP IYEGLLPDYT LPGLDPYAGT LIAGIVGTVI VLALGFALTR YARTA