ID   NIKMN_RHOCB             Reviewed;         347 AA.
AC   D5AQY8;
DT   27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT   15-JUN-2010, sequence version 1.
DT   25-MAY-2022, entry version 46.
DE   RecName: Full=Fused nickel transport protein NikMN;
DE   AltName: Full=Energy-coupling factor transporter probable substrate-capture protein NikMN;
DE            Short=ECF transporter S component NikMN;
GN   Name=nikMN; OrderedLocusNames=RCAP_rcc01034;
OS   Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhodobacterales;
OC   Rhodobacteraceae; Rhodobacter.
OX   NCBI_TaxID=272942;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=20418398; DOI=10.1128/jb.00366-10;
RA   Strnad H., Lapidus A., Paces J., Ulbrich P., Vlcek C., Paces V.,
RA   Haselkorn R.;
RT   "Complete genome sequence of the photosynthetic purple nonsulfur bacterium
RT   Rhodobacter capsulatus SB 1003.";
RL   J. Bacteriol. 192:3545-3546(2010).
RN   [2]
RP   FUNCTION IN NICKEL TRANSPORT, SUBSTRATES, SUBUNIT, AND EXPRESSION IN
RP   E.COLI.
RC   STRAIN=ATCC BAA-309 / NBRC 16581 / SB1003;
RX   PubMed=16352848; DOI=10.1128/jb.188.1.317-327.2006;
RA   Rodionov D.A., Hebbeln P., Gelfand M.S., Eitinger T.;
RT   "Comparative and functional genomic analysis of prokaryotic nickel and
RT   cobalt uptake transporters: evidence for a novel group of ATP-binding
RT   cassette transporters.";
RL   J. Bacteriol. 188:317-327(2006).
CC   -!- FUNCTION: Part of the energy-coupling factor (ECF) transporter complex
CC       NikMNQO involved in nickel import. The complex confers nickel uptake
CC       upon expression in E.coli; can also transport cobalt with a very low
CC       affinity. {ECO:0000269|PubMed:16352848}.
CC   -!- SUBUNIT: Forms an energy-coupling factor (ECF) transporter complex
CC       composed of an ATP-binding protein (A component, NikO), a transmembrane
CC       protein (T component, NikQ) and a fused possible substrate-capture
CC       protein (S component, NikMN) of unknown stoichimetry. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the CbiM family. NikM subfamily. {ECO:0000305}.
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DR   EMBL; CP001312; ADE84794.1; -; Genomic_DNA.
DR   RefSeq; WP_013066773.1; NC_014034.1.
DR   AlphaFoldDB; D5AQY8; -.
DR   SMR; D5AQY8; -.
DR   STRING; 272942.RCAP_rcc01034; -.
DR   TCDB; 3.A.1.23.7; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; ADE84794; ADE84794; RCAP_rcc01034.
DR   GeneID; 31489961; -.
DR   KEGG; rcp:RCAP_rcc01034; -.
DR   eggNOG; COG0310; Bacteria.
DR   HOGENOM; CLU_052508_2_0_5; -.
DR   OrthoDB; 1632785at2; -.
DR   Proteomes; UP000002361; Chromosome.
DR   GO; GO:0043190; C:ATP-binding cassette (ABC) transporter complex; IDA:UniProtKB.
DR   GO; GO:0015675; P:nickel cation transport; IDA:UniProtKB.
DR   InterPro; IPR002751; CbiM/NikMN.
DR   InterPro; IPR025937; PDGLE_dom.
DR   Pfam; PF01891; CbiM; 1.
DR   Pfam; PF13190; PDGLE; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Ion transport; Membrane; Nickel;
KW   Nickel transport; Reference proteome; Transmembrane; Transmembrane helix;
KW   Transport.
FT   CHAIN           1..347
FT                   /note="Fused nickel transport protein NikMN"
FT                   /id="PRO_0000411083"
FT   TRANSMEM        6..26
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        40..60
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        73..93
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        96..116
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        140..160
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        185..205
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        236..256
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        273..293
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        319..339
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   347 AA;  35244 MW;  0A49A6DEB20BBBD3 CRC64;
     MHIPDGYLSP VTCAVTFAAT VPFWYVSMRK LDRDLNGQHL PLVALVAAFS FVIMMFNLPI
     PGGTTAHAAG IGIAAVLLGP WAAVPAISVA LLIQAIFFGD GGITAFGANC LNMAVVGPMV
     AAAVYALGTR GAAIGSRRRV IMAGLASYAG LNAAALLAAV EFGVQPLFFH DAAGAPLYAP
     YPLSVAVPAM ALTHLTIAGA AEFIVTAGLV AWLQRSNPEL LAPRRAPAAP ERHLRLWAGI
     GALVVLCPLG LIAAGTAWGE WGAEDFTSEA GRAAMAGASG GVAPPAGLPG GFARLAELWS
     APLPDYAPAF VQNAPLGYVL SALLGVALIV AGIGLSAGLR ALTRRAG