NIMI1_ARATH
ID NIMI1_ARATH Reviewed; 142 AA.
AC Q9FNZ5; Q9FWX4;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 109.
DE RecName: Full=Protein NIM1-INTERACTING 1;
DE Short=Protein NIMIN-1;
GN Name=NIMIN-1; OrderedLocusNames=At1g02450; ORFNames=T14P4.19, T6A9_28;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], INTERACTION WITH NPR1, INDUCTION, AND
RP SUBCELLULAR LOCATION.
RC STRAIN=cv. Columbia;
RX PubMed=11442055; DOI=10.1023/a:1010652620115;
RA Weigel R.R., Baeuscher C., Pfitzner A.J.P., Pfitzner U.M.;
RT "NIMIN-1, NIMIN-2 and NIMIN-3, members of a novel family of proteins from
RT Arabidopsis that interact with NPR1/NIM1, a key regulator of systemic
RT acquired resistance in plants.";
RL Plant Mol. Biol. 46:143-160(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- SUBUNIT: Interacts with NPR1. {ECO:0000269|PubMed:11442055}.
CC -!- INTERACTION:
CC Q9FNZ5; B2GVM8: At1g24230; NbExp=3; IntAct=EBI-541099, EBI-15195391;
CC Q9FNZ5; A0A178VXH5: At2g43220; NbExp=3; IntAct=EBI-541099, EBI-25511288;
CC Q9FNZ5; Q9FN69: GL3; NbExp=3; IntAct=EBI-541099, EBI-533348;
CC Q9FNZ5; P93002: NPR1; NbExp=4; IntAct=EBI-541099, EBI-1392127;
CC Q9FNZ5; Q8L9W4: NPR1; NbExp=5; IntAct=EBI-541099, EBI-541093;
CC Q9FNZ5; Q8L746: NPR3; NbExp=4; IntAct=EBI-541099, EBI-4441365;
CC Q9FNZ5; Q9C9L2: TCP15; NbExp=3; IntAct=EBI-541099, EBI-4426144;
CC Q9FNZ5; Q9MAH8: TCP3; NbExp=3; IntAct=EBI-541099, EBI-25522447;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:11442055}.
CC -!- INDUCTION: By salicylic acid (SA) and BTH.
CC {ECO:0000269|PubMed:11442055}.
CC -!- SIMILARITY: Belongs to the NPR1-interactor family.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG10641.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AJ250184; CAC19844.1; -; mRNA.
DR EMBL; AC022521; AAG10641.1; ALT_INIT; Genomic_DNA.
DR EMBL; AC064879; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002684; AEE27431.1; -; Genomic_DNA.
DR EMBL; AK119149; BAC43719.1; -; mRNA.
DR EMBL; BT003662; AAO39890.1; -; mRNA.
DR PIR; A86155; A86155.
DR RefSeq; NP_563653.2; NM_100126.4.
DR AlphaFoldDB; Q9FNZ5; -.
DR SMR; Q9FNZ5; -.
DR BioGRID; 23040; 8.
DR IntAct; Q9FNZ5; 11.
DR STRING; 3702.AT1G02450.1; -.
DR PaxDb; Q9FNZ5; -.
DR PRIDE; Q9FNZ5; -.
DR ProteomicsDB; 251298; -.
DR EnsemblPlants; AT1G02450.1; AT1G02450.1; AT1G02450.
DR GeneID; 837800; -.
DR Gramene; AT1G02450.1; AT1G02450.1; AT1G02450.
DR KEGG; ath:AT1G02450; -.
DR Araport; AT1G02450; -.
DR TAIR; locus:2196065; AT1G02450.
DR eggNOG; ENOG502R1UH; Eukaryota.
DR HOGENOM; CLU_1837849_0_0_1; -.
DR InParanoid; Q9FNZ5; -.
DR OMA; PAFRWED; -.
DR OrthoDB; 1612750at2759; -.
DR PRO; PR:Q9FNZ5; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FNZ5; baseline and differential.
DR Genevisible; Q9FNZ5; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0042742; P:defense response to bacterium; IMP:TAIR.
DR GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IMP:TAIR.
DR GO; GO:0010112; P:regulation of systemic acquired resistance; IMP:TAIR.
DR InterPro; IPR034578; NIMIN-1.
DR InterPro; IPR031425; NPR1/NH1-interacting.
DR PANTHER; PTHR33669; PTHR33669; 1.
DR PANTHER; PTHR33669:SF11; PTHR33669:SF11; 1.
DR Pfam; PF15699; NPR1_interact; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Nucleus; Reference proteome.
FT CHAIN 1..142
FT /note="Protein NIM1-INTERACTING 1"
FT /id="PRO_0000407996"
FT REGION 47..53
FT /note="Involved in NPR1/NIM1 interaction"
FT REGION 63..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 108..142
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 110..141
FT /evidence="ECO:0000255"
FT MOTIF 60..64
FT /note="Nuclear localization signal"
FT /evidence="ECO:0000255"
FT COMPBIAS 109..136
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 142 AA; 16818 MW; 5C8EB7C4A7064B65 CRC64;
MYPKQFSLYN YSLETMSKDE NVESKETIRV DKRVREDEEE EEEKKIDTFF KLIKHYQEAR
KRRREELAEN SGVVRRKSNG GERSGIVVPA FQPEDFSQCR TGLKPPLMFV SDHKEENTKV
EQEEDQTEER NEDKALDLNL AL
