NIP14_ORYSJ
ID NIP14_ORYSJ Reviewed; 273 AA.
AC Q5Z9E2; A0A0P0WY81;
DT 01-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 94.
DE RecName: Full=Aquaporin NIP1-4;
DE AltName: Full=NOD26-like intrinsic protein 1-4;
DE AltName: Full=OsNIP1;4;
GN Name=NIP1-4; OrderedLocusNames=Os06g0552700, LOC_Os06g35930;
GN ORFNames=P0427B07.13;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [3]
RP NOMENCLATURE, AND TISSUE SPECIFICITY.
RX PubMed=16033806; DOI=10.1093/pcp/pci172;
RA Sakurai J., Ishikawa F., Yamaguchi T., Uemura M., Maeshima M.;
RT "Identification of 33 rice aquaporin genes and analysis of their expression
RT and function.";
RL Plant Cell Physiol. 46:1568-1577(2005).
CC -!- FUNCTION: Aquaporins facilitate the transport of water and small
CC neutral solutes across cell membranes. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in leaves. {ECO:0000269|PubMed:16033806}.
CC -!- DOMAIN: Aquaporins contain two tandem repeats each containing three
CC membrane-spanning domains and a pore-forming loop with the signature
CC motif Asn-Pro-Ala (NPA).
CC -!- SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family. NIP (TC
CC 1.A.8.12) subfamily. {ECO:0000305}.
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DR EMBL; AP003682; BAD53665.1; -; Genomic_DNA.
DR EMBL; AP014962; BAS98200.1; -; Genomic_DNA.
DR RefSeq; XP_015642749.1; XM_015787263.1.
DR AlphaFoldDB; Q5Z9E2; -.
DR SMR; Q5Z9E2; -.
DR STRING; 4530.OS06T0552700-01; -.
DR PaxDb; Q5Z9E2; -.
DR PRIDE; Q5Z9E2; -.
DR EnsemblPlants; Os06t0552700-01; Os06t0552700-01; Os06g0552700.
DR GeneID; 107276403; -.
DR Gramene; Os06t0552700-01; Os06t0552700-01; Os06g0552700.
DR KEGG; osa:107276403; -.
DR eggNOG; KOG0223; Eukaryota.
DR HOGENOM; CLU_020019_3_1_1; -.
DR InParanoid; Q5Z9E2; -.
DR OMA; YLMFVIM; -.
DR OrthoDB; 1152704at2759; -.
DR Proteomes; UP000000763; Chromosome 6.
DR Proteomes; UP000059680; Chromosome 6.
DR Genevisible; Q5Z9E2; OS.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0015267; F:channel activity; IEA:InterPro.
DR Gene3D; 1.20.1080.10; -; 1.
DR InterPro; IPR023271; Aquaporin-like.
DR InterPro; IPR034294; Aquaporin_transptr.
DR InterPro; IPR000425; MIP.
DR InterPro; IPR022357; MIP_CS.
DR PANTHER; PTHR45724; PTHR45724; 1.
DR Pfam; PF00230; MIP; 1.
DR PRINTS; PR00783; MINTRINSICP.
DR SUPFAM; SSF81338; SSF81338; 1.
DR TIGRFAMs; TIGR00861; MIP; 1.
DR PROSITE; PS00221; MIP; 1.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Repeat; Transmembrane; Transmembrane helix;
KW Transport.
FT CHAIN 1..273
FT /note="Aquaporin NIP1-4"
FT /id="PRO_0000286029"
FT TRANSMEM 59..79
FT /note="Helical; Name=1"
FT /evidence="ECO:0000255"
FT TRANSMEM 86..106
FT /note="Helical; Name=2"
FT /evidence="ECO:0000255"
FT TRANSMEM 133..155
FT /note="Helical; Name=3"
FT /evidence="ECO:0000255"
FT TRANSMEM 174..194
FT /note="Helical; Name=4"
FT /evidence="ECO:0000255"
FT TRANSMEM 198..218
FT /note="Helical; Name=5"
FT /evidence="ECO:0000255"
FT TRANSMEM 245..265
FT /note="Helical; Name=6"
FT /evidence="ECO:0000255"
FT MOTIF 115..117
FT /note="NPA 1"
FT MOTIF 227..229
FT /note="NPA 2"
SQ SEQUENCE 273 AA; 28402 MW; 9FE6A789576DA44F CRC64;
MARREVDDSY TNGSVVEVVS IEEGSKMDKE DDHQNPQAPD GGDVVVCGMP MSFTFLQMLL
AEFLATFFLM FAGLGAITVE EKKGAVTFPG VAVAWGAAVM AMVYAVGHVS GAHLNPAVTL
GFAVAGRFPW RRAPAYALAQ TAAATAASVV LRLMFGGRHA PVPATLPGGA HAQSLVIEFV
ITFYLMFVIM AVATDDQAVG HMAGVAVGGT IMLNVLFAGP VSGASMNPAR SIGPALVGSK
YTALWVYILG PFAGAAAGAW AYSLIRLTGD RTD
