ID   NIP7_XENTR              Reviewed;         180 AA.
AC   A4QND5;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   15-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=60S ribosome subunit biogenesis protein NIP7 homolog;
GN   Name=nip7;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for proper 34S pre-rRNA processing and 60S ribosome
CC       subunit assembly. {ECO:0000250}.
CC   -!- SUBUNIT: Monomer. Interacts with pre-ribosome complex. May bind to RNA.
CC       Interacts with NOL8. Interacts with FTSJ3 (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the NIP7 family. {ECO:0000305}.
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DR   EMBL; BC135468; AAI35469.1; -; mRNA.
DR   RefSeq; NP_001096512.1; NM_001103042.1.
DR   AlphaFoldDB; A4QND5; -.
DR   SMR; A4QND5; -.
DR   STRING; 8364.ENSXETP00000038700; -.
DR   PaxDb; A4QND5; -.
DR   DNASU; 100125143; -.
DR   GeneID; 100125143; -.
DR   KEGG; xtr:100125143; -.
DR   CTD; 51388; -.
DR   Xenbase; XB-GENE-1005412; nip7.
DR   eggNOG; KOG3492; Eukaryota.
DR   HOGENOM; CLU_097217_0_0_1; -.
DR   InParanoid; A4QND5; -.
DR   OMA; FLCGNHV; -.
DR   OrthoDB; 1405073at2759; -.
DR   PhylomeDB; A4QND5; -.
DR   TreeFam; TF300081; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProt.
DR   GO; GO:0030687; C:preribosome, large subunit precursor; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0042273; P:ribosomal large subunit biogenesis; IBA:GO_Central.
DR   GO; GO:0042255; P:ribosome assembly; IEA:InterPro.
DR   Gene3D; 2.30.130.10; -; 1.
DR   InterPro; IPR002478; PUA.
DR   InterPro; IPR015947; PUA-like_sf.
DR   InterPro; IPR036974; PUA_sf.
DR   InterPro; IPR016686; Ribosomal_synth_fac_NIP7.
DR   InterPro; IPR040598; UPF0113_N.
DR   InterPro; IPR005155; UPF0113_PUA.
DR   Pfam; PF03657; UPF0113; 1.
DR   Pfam; PF17833; UPF0113_N; 1.
DR   PIRSF; PIRSF017190; Rbsml_synth_fac_NIP7; 1.
DR   SMART; SM00359; PUA; 1.
DR   SUPFAM; SSF88697; SSF88697; 1.
DR   PROSITE; PS50890; PUA; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Ribosome biogenesis; RNA-binding.
FT   CHAIN           1..180
FT                   /note="60S ribosome subunit biogenesis protein NIP7
FT                   homolog"
FT                   /id="PRO_0000355570"
FT   DOMAIN          94..170
FT                   /note="PUA"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00161"
FT   REGION          1..92
FT                   /note="N-terminal domain"
FT                   /evidence="ECO:0000250"
FT   REGION          93..180
FT                   /note="C-terminal domain"
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   180 AA;  20532 MW;  2CD11D5321B5759E CRC64;
     MRPLTDEETK AMFEKLSKYI GENIKLLVDR PDGTYCFRLH NDRVYYVSER ILKLATNIAR
     DKLVSLGTCF GKFTKTHKFR LHVTALDYLA PYAKYKVWVK PGAEQSFLYG NHVLKSGLGR
     ITENTSQYQG VVVYSMADIP LGFGVAAKST QECRKLDPMA IVVFHQADVG EYIRHEDTLT