NIRC_PSEAE
ID NIRC_PSEAE Reviewed; 119 AA.
AC Q51479;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 117.
DE RecName: Full=Cytochrome c55X;
DE Flags: Precursor;
GN Name=nirC; OrderedLocusNames=PA0517;
OS Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS 14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208964;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=8566817; DOI=10.1016/0378-1119(95)00641-9;
RA Kawasaki S., Arai H., Igarashi Y., Kodama T.;
RT "Sequencing and characterization of the downstream region of the genes
RT encoding nitrite reductase and cytochrome c-551 (nirSM) from Pseudomonas
RT aeruginosa: identification of the gene necessary for biosynthesis of heme
RT d1.";
RL Gene 167:87-91(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC PRS 101 / PAO1;
RX PubMed=10984043; DOI=10.1038/35023079;
RA Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT pathogen.";
RL Nature 406:959-964(2000).
CC -!- FUNCTION: Monoheme c-type cytochrome.
CC -!- SUBCELLULAR LOCATION: Periplasm.
CC -!- PTM: Binds 1 heme c group covalently per subunit.
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DR EMBL; D50473; BAA09065.1; -; Genomic_DNA.
DR EMBL; AE004091; AAG03906.1; -; Genomic_DNA.
DR PIR; JC4552; JC4552.
DR RefSeq; NP_249208.1; NC_002516.2.
DR RefSeq; WP_003084870.1; NZ_QZGE01000010.1.
DR PDB; 6TP9; X-ray; 2.19 A; A/B/C/D/E/F/G/H/I/J/K=32-119.
DR PDBsum; 6TP9; -.
DR AlphaFoldDB; Q51479; -.
DR SMR; Q51479; -.
DR STRING; 287.DR97_3485; -.
DR PaxDb; Q51479; -.
DR EnsemblBacteria; AAG03906; AAG03906; PA0517.
DR GeneID; 879462; -.
DR KEGG; pae:PA0517; -.
DR PATRIC; fig|208964.12.peg.547; -.
DR PseudoCAP; PA0517; -.
DR HOGENOM; CLU_159748_0_0_6; -.
DR OMA; DCGACHG; -.
DR BioCyc; PAER208964:G1FZ6-522-MON; -.
DR PHI-base; PHI:5444; -.
DR Proteomes; UP000002438; Chromosome.
DR GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0020037; F:heme binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.10.760.10; -; 1.
DR InterPro; IPR009056; Cyt_c-like_dom.
DR InterPro; IPR036909; Cyt_c-like_dom_sf.
DR Pfam; PF13442; Cytochrome_CBB3; 1.
DR SUPFAM; SSF46626; SSF46626; 1.
DR PROSITE; PS51007; CYTC; 1.
PE 1: Evidence at protein level;
KW 3D-structure; Electron transport; Heme; Iron; Metal-binding; Periplasm;
KW Reference proteome; Signal; Transport.
FT SIGNAL 1..20
FT /evidence="ECO:0000255"
FT CHAIN 21..119
FT /note="Cytochrome c55X"
FT /id="PRO_0000006572"
FT BINDING 51
FT /ligand="heme c"
FT /ligand_id="ChEBI:CHEBI:61717"
FT /note="covalent"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT BINDING 54
FT /ligand="heme c"
FT /ligand_id="ChEBI:CHEBI:61717"
FT /note="covalent"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT BINDING 55
FT /ligand="heme c"
FT /ligand_id="ChEBI:CHEBI:61717"
FT /ligand_part="Fe"
FT /ligand_part_id="ChEBI:CHEBI:18248"
FT /note="axial binding residue"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00433"
FT HELIX 37..49
FT /evidence="ECO:0007829|PDB:6TP9"
FT HELIX 51..54
FT /evidence="ECO:0007829|PDB:6TP9"
FT STRAND 57..59
FT /evidence="ECO:0007829|PDB:6TP9"
FT STRAND 61..64
FT /evidence="ECO:0007829|PDB:6TP9"
FT TURN 69..74
FT /evidence="ECO:0007829|PDB:6TP9"
FT HELIX 77..86
FT /evidence="ECO:0007829|PDB:6TP9"
FT TURN 97..99
FT /evidence="ECO:0007829|PDB:6TP9"
FT HELIX 102..113
FT /evidence="ECO:0007829|PDB:6TP9"
SQ SEQUENCE 119 AA; 12801 MW; C21F43F00B71B4BA CRC64;
MNAPPDFRRA ASHALWLALA LTFACPLPGL ADEHPDARRQ AQLRHLLLQD CGSCHGLRLT
GGLGPALTPE ALRGKPRESL VATVLMGRPQ TPMPPWAGLL SEDDAGWLVD RLIEGEIAP
