ID   NIRD_SALTI              Reviewed;         108 AA.
AC   P0A230; P40789;
DT   01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Nitrite reductase (NADH) small subunit;
DE            EC=1.7.1.15;
GN   Name=nirD; OrderedLocusNames=STY4321, t4030;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Required for activity of the reductase. {ECO:0000250}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=2 H2O + 3 NAD(+) + NH4(+) = 5 H(+) + 3 NADH + nitrite;
CC         Xref=Rhea:RHEA:24628, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:16301, ChEBI:CHEBI:28938, ChEBI:CHEBI:57540,
CC         ChEBI:CHEBI:57945; EC=1.7.1.15;
CC   -!- SUBUNIT: Associates with NirB. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; AL513382; CAD08138.1; -; Genomic_DNA.
DR   EMBL; AE014613; AAO71499.1; -; Genomic_DNA.
DR   RefSeq; NP_458427.1; NC_003198.1.
DR   RefSeq; WP_000084814.1; NZ_WSUR01000001.1.
DR   AlphaFoldDB; P0A230; -.
DR   SMR; P0A230; -.
DR   STRING; 220341.16505116; -.
DR   EnsemblBacteria; AAO71499; AAO71499; t4030.
DR   KEGG; stt:t4030; -.
DR   KEGG; sty:STY4321; -.
DR   PATRIC; fig|220341.7.peg.4416; -.
DR   eggNOG; COG2146; Bacteria.
DR   HOGENOM; CLU_055690_3_0_6; -.
DR   OMA; IDNRDPF; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0106316; F:nitrite reductase NADH activity; IEA:RHEA.
DR   GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR   CDD; cd03529; Rieske_NirD; 1.
DR   Gene3D; 2.102.10.10; -; 1.
DR   InterPro; IPR017881; NirD.
DR   InterPro; IPR012748; Rieske-like_NirD.
DR   InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR   PANTHER; PTHR40562; PTHR40562; 1.
DR   Pfam; PF13806; Rieske_2; 1.
DR   SUPFAM; SSF50022; SSF50022; 1.
DR   TIGRFAMs; TIGR02378; nirD_assim_sml; 1.
DR   PROSITE; PS51300; NIRD; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; NAD; Nitrate assimilation; Oxidoreductase.
FT   CHAIN           1..108
FT                   /note="Nitrite reductase (NADH) small subunit"
FT                   /id="PRO_0000096856"
SQ   SEQUENCE   108 AA;  12097 MW;  375C6D13AFF98161 CRC64;
     MSQWQNICKI DDILPGTGVC ALSGGEQVAI FRPYHSDQVF AISNIDPFFE ASVLSRGLIA
     EHQGELWVAS PLKKQRFRLS DGLCMEDEQF SVKHYDARVK DGVVQLRG