NIRD_SALTY
ID NIRD_SALTY Reviewed; 108 AA.
AC P0A229; P40789;
DT 01-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2005, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Nitrite reductase (NADH) small subunit;
DE EC=1.7.1.15;
GN Name=nirD; OrderedLocusNames=STM3475;
OS Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Salmonella.
OX NCBI_TaxID=99287;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX PubMed=11677609; DOI=10.1038/35101614;
RA McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA Wilson R.K.;
RT "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL Nature 413:852-856(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 42-108.
RC STRAIN=LT2;
RX PubMed=1987123; DOI=10.1128/jb.173.1.325-333.1991;
RA Wu J.Y., Siegel L.M., Kredich N.M.;
RT "High-level expression of Escherichia coli NADPH-sulfite reductase:
RT requirement for a cloned cysG plasmid to overcome limiting siroheme
RT cofactor.";
RL J. Bacteriol. 173:325-333(1991).
CC -!- FUNCTION: Required for activity of the reductase.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=2 H2O + 3 NAD(+) + NH4(+) = 5 H(+) + 3 NADH + nitrite;
CC Xref=Rhea:RHEA:24628, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:16301, ChEBI:CHEBI:28938, ChEBI:CHEBI:57540,
CC ChEBI:CHEBI:57945; EC=1.7.1.15;
CC -!- SUBUNIT: Associates with NirB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE006468; AAL22337.1; -; Genomic_DNA.
DR EMBL; M64606; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; NP_462378.1; NC_003197.2.
DR RefSeq; WP_000084814.1; NC_003197.2.
DR AlphaFoldDB; P0A229; -.
DR SMR; P0A229; -.
DR STRING; 99287.STM3475; -.
DR PaxDb; P0A229; -.
DR EnsemblBacteria; AAL22337; AAL22337; STM3475.
DR GeneID; 1254998; -.
DR KEGG; stm:STM3475; -.
DR PATRIC; fig|99287.12.peg.3673; -.
DR HOGENOM; CLU_055690_3_0_6; -.
DR OMA; IDNRDPF; -.
DR PhylomeDB; P0A229; -.
DR BioCyc; SENT99287:STM3475-MON; -.
DR Proteomes; UP000001014; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009344; C:nitrite reductase complex [NAD(P)H]; IBA:GO_Central.
DR GO; GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:InterPro.
DR GO; GO:0008942; F:nitrite reductase [NAD(P)H] activity; IBA:GO_Central.
DR GO; GO:0106316; F:nitrite reductase NADH activity; IEA:RHEA.
DR GO; GO:0009061; P:anaerobic respiration; IBA:GO_Central.
DR GO; GO:0042128; P:nitrate assimilation; IEA:UniProtKB-KW.
DR CDD; cd03529; Rieske_NirD; 1.
DR Gene3D; 2.102.10.10; -; 1.
DR InterPro; IPR017881; NirD.
DR InterPro; IPR012748; Rieske-like_NirD.
DR InterPro; IPR036922; Rieske_2Fe-2S_sf.
DR PANTHER; PTHR40562; PTHR40562; 1.
DR Pfam; PF13806; Rieske_2; 1.
DR SUPFAM; SSF50022; SSF50022; 1.
DR TIGRFAMs; TIGR02378; nirD_assim_sml; 1.
DR PROSITE; PS51300; NIRD; 1.
PE 4: Predicted;
KW Cytoplasm; NAD; Nitrate assimilation; Oxidoreductase; Reference proteome.
FT CHAIN 1..108
FT /note="Nitrite reductase (NADH) small subunit"
FT /id="PRO_0000096857"
FT CONFLICT 76
FT /note="R -> P (in Ref. 2)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 108 AA; 12097 MW; 375C6D13AFF98161 CRC64;
MSQWQNICKI DDILPGTGVC ALSGGEQVAI FRPYHSDQVF AISNIDPFFE ASVLSRGLIA
EHQGELWVAS PLKKQRFRLS DGLCMEDEQF SVKHYDARVK DGVVQLRG
