NJMU_MOUSE
ID NJMU_MOUSE Reviewed; 393 AA.
AC Q9CYI0; Q7TMQ9;
DT 04-MAY-2001, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 2.
DT 03-AUG-2022, entry version 110.
DE RecName: Full=Protein Njmu-R1;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Bone marrow, and Muellerian duct;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J;
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Mammary tumor;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
RN [4]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC TISSUE=Brain, Brown adipose tissue, Kidney, Lung, Pancreas, Spleen, and
RC Testis;
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [5]
RP INTERACTION WITH TBC1D23.
RX PubMed=29084197; DOI=10.1038/ncb3627;
RA Shin J.J.H., Gillingham A.K., Begum F., Chadwick J., Munro S.;
RT "TBC1D23 is a bridging factor for endosomal vesicle capture by golgins at
RT the trans-Golgi.";
RL Nat. Cell Biol. 19:1424-1432(2017).
CC -!- FUNCTION: May have a role in spermatogenesis. {ECO:0000250}.
CC -!- SUBUNIT: Interacts with TBC1D23; this interaction may be indirect.
CC {ECO:0000269|PubMed:29084197}.
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DR EMBL; AK135352; BAE22498.1; -; mRNA.
DR EMBL; AK153246; BAE31837.1; -; mRNA.
DR EMBL; AL591146; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC055024; AAH55024.1; -; mRNA.
DR CCDS; CCDS25132.1; -.
DR RefSeq; NP_081748.1; NM_027472.3.
DR AlphaFoldDB; Q9CYI0; -.
DR SMR; Q9CYI0; -.
DR STRING; 10090.ENSMUSP00000099515; -.
DR iPTMnet; Q9CYI0; -.
DR PhosphoSitePlus; Q9CYI0; -.
DR EPD; Q9CYI0; -.
DR MaxQB; Q9CYI0; -.
DR PaxDb; Q9CYI0; -.
DR PRIDE; Q9CYI0; -.
DR Antibodypedia; 1366; 191 antibodies from 22 providers.
DR DNASU; 70591; -.
DR Ensembl; ENSMUST00000103225; ENSMUSP00000099515; ENSMUSG00000057181.
DR GeneID; 70591; -.
DR KEGG; mmu:70591; -.
DR UCSC; uc007klv.2; mouse.
DR MGI; MGI:1917841; 5730455P16Rik.
DR VEuPathDB; HostDB:ENSMUSG00000057181; -.
DR eggNOG; ENOG502QRCR; Eukaryota.
DR GeneTree; ENSGT00390000005481; -.
DR InParanoid; Q9CYI0; -.
DR OMA; LFEGMGN; -.
DR OrthoDB; 1351924at2759; -.
DR PhylomeDB; Q9CYI0; -.
DR TreeFam; TF330763; -.
DR BioGRID-ORCS; 70591; 2 hits in 71 CRISPR screens.
DR PRO; PR:Q9CYI0; -.
DR Proteomes; UP000000589; Chromosome 11.
DR RNAct; Q9CYI0; protein.
DR Bgee; ENSMUSG00000057181; Expressed in hindlimb stylopod muscle and 218 other tissues.
DR ExpressionAtlas; Q9CYI0; baseline and differential.
DR Genevisible; Q9CYI0; MM.
DR GO; GO:0031410; C:cytoplasmic vesicle; ISO:MGI.
DR GO; GO:0005802; C:trans-Golgi network; ISO:MGI.
DR GO; GO:0006886; P:intracellular protein transport; ISO:MGI.
DR GO; GO:0099041; P:vesicle tethering to Golgi; ISO:MGI.
DR InterPro; IPR028280; Njmu-R1.
DR PANTHER; PTHR14416; PTHR14416; 1.
DR Pfam; PF15053; Njmu-R1; 1.
PE 1: Evidence at protein level;
KW Phosphoprotein; Reference proteome.
FT CHAIN 1..393
FT /note="Protein Njmu-R1"
FT /id="PRO_0000096866"
FT REGION 1..74
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 8
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9HAS0"
FT MOD_RES 18
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9HAS0"
SQ SEQUENCE 393 AA; 44422 MW; 336D40805D12169A CRC64;
MLPSLQESLD GDEKELESSE EGGSAEERRL EPPPSSHYCL YSFRGSRLTQ NRGDSDDGRS
GGINAETPSG DDFSLSLVDT NLPSEVEPEL RSFIAKRLSK GAVFEGLGNV ASVELRIPGY
RVGCYYCLFQ QEKLLPEIAA MESEHNPSEY VVCFLGGSEK GLELFRLELD KYIQGLKNNM
NCEERSLGND VKSYLNSWYE DVVCPIQRVV LLFQEKLTFL LHAALSYTPV EFKESDEKTK
RDINRFLSVA SLQGLIHEGT MTSLCMAMTE EQHKSVIIDC SGPQPQFHNA GSNRFCEDWM
QAFLHGAEAG NPFLFRQVLE NFKLKAIQDT NNLKRFIRQA EMNHYALFKC YMFLKNCGSG
DILLKIVKVE HEEMPEAKSV VAVLEEFMRE ALV
