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NKAI1_DANRE
ID   NKAI1_DANRE             Reviewed;         207 AA.
AC   Q6PHL4;
DT   13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 89.
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1;
GN   Name=nkain1; ORFNames=zgc:65908;
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Zebrafish Gene Collection (ZGC) project;
RL   Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with atp1b1 C-terminus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NKAIN family. {ECO:0000305}.
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DR   EMBL; BC056509; AAH56509.1; -; mRNA.
DR   RefSeq; NP_956839.1; NM_200545.1.
DR   AlphaFoldDB; Q6PHL4; -.
DR   SMR; Q6PHL4; -.
DR   STRING; 7955.ENSDARP00000003013; -.
DR   PaxDb; Q6PHL4; -.
DR   Ensembl; ENSDART00000015632; ENSDARP00000003013; ENSDARG00000006859.
DR   Ensembl; ENSDART00000182608; ENSDARP00000148785; ENSDARG00000006859.
DR   GeneID; 393517; -.
DR   KEGG; dre:393517; -.
DR   CTD; 79570; -.
DR   ZFIN; ZDB-GENE-040426-1472; nkain1.
DR   eggNOG; KOG4556; Eukaryota.
DR   GeneTree; ENSGT00940000159949; -.
DR   HOGENOM; CLU_090781_0_0_1; -.
DR   InParanoid; Q6PHL4; -.
DR   OMA; KYLIMYA; -.
DR   OrthoDB; 1281511at2759; -.
DR   PhylomeDB; Q6PHL4; -.
DR   TreeFam; TF321348; -.
DR   PRO; PR:Q6PHL4; -.
DR   Proteomes; UP000000437; Genome assembly.
DR   Proteomes; UP000814640; Chromosome 19.
DR   Bgee; ENSDARG00000006859; Expressed in mature ovarian follicle and 28 other tissues.
DR   ExpressionAtlas; Q6PHL4; baseline and differential.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IBA:GO_Central.
DR   InterPro; IPR008516; Na/K-Atpase_Interacting.
DR   PANTHER; PTHR13084; PTHR13084; 1.
DR   Pfam; PF05640; NKAIN; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..207
FT                   /note="Sodium/potassium-transporting ATPase subunit beta-1-
FT                   interacting protein 1"
FT                   /id="PRO_0000310467"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        100
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  23610 MW;  2F22C79A1DFD54A2 CRC64;
     MGRCDGRCTL VVICCLQLVA ALQRQVFDFM GYQWAPILAN FLHIMAVILG VFGTVQVRSR
     YLILYAVWLV VWVGWNSFII CFYLEVGHLS QDRDFLMTFN TSLHRSWWME NGPGCLVTPV
     PDSPLAPQDH HVITVSGCLL DYQYIEVVSS ALQVFLALFG FVYACYVSKY SPDDEDSFDF
     FDGLGSYNYQ PPQKISQLQL RPLYTTG
 
 
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