NKAI1_DANRE
ID NKAI1_DANRE Reviewed; 207 AA.
AC Q6PHL4;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1;
DE Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1;
GN Name=nkain1; ORFNames=zgc:65908;
OS Danio rerio (Zebrafish) (Brachydanio rerio).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC Danionidae; Danioninae; Danio.
OX NCBI_TaxID=7955;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Zebrafish Gene Collection (ZGC) project;
RL Submitted (AUG-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with atp1b1 C-terminus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NKAIN family. {ECO:0000305}.
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DR EMBL; BC056509; AAH56509.1; -; mRNA.
DR RefSeq; NP_956839.1; NM_200545.1.
DR AlphaFoldDB; Q6PHL4; -.
DR SMR; Q6PHL4; -.
DR STRING; 7955.ENSDARP00000003013; -.
DR PaxDb; Q6PHL4; -.
DR Ensembl; ENSDART00000015632; ENSDARP00000003013; ENSDARG00000006859.
DR Ensembl; ENSDART00000182608; ENSDARP00000148785; ENSDARG00000006859.
DR GeneID; 393517; -.
DR KEGG; dre:393517; -.
DR CTD; 79570; -.
DR ZFIN; ZDB-GENE-040426-1472; nkain1.
DR eggNOG; KOG4556; Eukaryota.
DR GeneTree; ENSGT00940000159949; -.
DR HOGENOM; CLU_090781_0_0_1; -.
DR InParanoid; Q6PHL4; -.
DR OMA; KYLIMYA; -.
DR OrthoDB; 1281511at2759; -.
DR PhylomeDB; Q6PHL4; -.
DR TreeFam; TF321348; -.
DR PRO; PR:Q6PHL4; -.
DR Proteomes; UP000000437; Genome assembly.
DR Proteomes; UP000814640; Chromosome 19.
DR Bgee; ENSDARG00000006859; Expressed in mature ovarian follicle and 28 other tissues.
DR ExpressionAtlas; Q6PHL4; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002028; P:regulation of sodium ion transport; IBA:GO_Central.
DR InterPro; IPR008516; Na/K-Atpase_Interacting.
DR PANTHER; PTHR13084; PTHR13084; 1.
DR Pfam; PF05640; NKAIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..207
FT /note="Sodium/potassium-transporting ATPase subunit beta-1-
FT interacting protein 1"
FT /id="PRO_0000310467"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 147..167
FT /note="Helical"
FT /evidence="ECO:0000255"
FT CARBOHYD 100
FT /note="N-linked (GlcNAc...) asparagine"
FT /evidence="ECO:0000255"
SQ SEQUENCE 207 AA; 23610 MW; 2F22C79A1DFD54A2 CRC64;
MGRCDGRCTL VVICCLQLVA ALQRQVFDFM GYQWAPILAN FLHIMAVILG VFGTVQVRSR
YLILYAVWLV VWVGWNSFII CFYLEVGHLS QDRDFLMTFN TSLHRSWWME NGPGCLVTPV
PDSPLAPQDH HVITVSGCLL DYQYIEVVSS ALQVFLALFG FVYACYVSKY SPDDEDSFDF
FDGLGSYNYQ PPQKISQLQL RPLYTTG