ID   NKAI1_XENTR             Reviewed;         207 AA.
AC   Q0IHU6; A4IHR6;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1;
DE            Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 1;
DE   AltName: Full=Protein FAM77C;
GN   Name=nkain1; Synonyms=fam77c;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain, and Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBUNIT: Interacts with atp1b1 C-terminus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the NKAIN family. {ECO:0000305}.
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DR   EMBL; BC122964; AAI22965.1; -; mRNA.
DR   EMBL; BC135653; AAI35654.1; -; mRNA.
DR   RefSeq; NP_001072596.1; NM_001079128.1.
DR   AlphaFoldDB; Q0IHU6; -.
DR   PaxDb; Q0IHU6; -.
DR   DNASU; 780051; -.
DR   GeneID; 780051; -.
DR   KEGG; xtr:780051; -.
DR   CTD; 79570; -.
DR   Xenbase; XB-GENE-946558; nkain1.
DR   eggNOG; KOG4556; Eukaryota.
DR   HOGENOM; CLU_090781_0_0_1; -.
DR   InParanoid; Q0IHU6; -.
DR   OMA; KYLIMYA; -.
DR   OrthoDB; 1281511at2759; -.
DR   PhylomeDB; Q0IHU6; -.
DR   TreeFam; TF321348; -.
DR   Proteomes; UP000008143; Chromosome 2.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000012908; Expressed in embryo and 2 other tissues.
DR   ExpressionAtlas; Q0IHU6; baseline.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0002028; P:regulation of sodium ion transport; IBA:GO_Central.
DR   InterPro; IPR008516; Na/K-Atpase_Interacting.
DR   PANTHER; PTHR13084; PTHR13084; 1.
DR   Pfam; PF05640; NKAIN; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Glycoprotein; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix.
FT   CHAIN           1..207
FT                   /note="Sodium/potassium-transporting ATPase subunit beta-1-
FT                   interacting protein 1"
FT                   /id="PRO_0000263646"
FT   TRANSMEM        2..22
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        62..82
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        147..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        100
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   207 AA;  23670 MW;  B1C191EDEC1D5FFD CRC64;
     MGRCSGRCTL VGICCLQLAA ALQRQIFDFL GYQWAPILAN FLHIMVVILG ILGTLHYRSR
     YLILYSIWLA LWVAWNAFII CFYLEVGHFS QHRDLIMNFN TSMHRSWWME NGPGCLVTPV
     RGPPLPLADH HMVTVTGCLL DYPYIEALSS ALQIFLALFG FVYACYVSKV FMDEEDSFDF
     IGSYDSYGYQ APMKTSHLQL QPLYKPG