NKAI3_XENTR
ID NKAI3_XENTR Reviewed; 181 AA.
AC Q0VFH9;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2006, sequence version 1.
DT 03-AUG-2022, entry version 60.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 3;
DE Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 3;
GN Name=nkain3;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with atp1b1 C-terminus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NKAIN family. {ECO:0000305}.
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DR EMBL; BC118822; AAI18823.1; -; mRNA.
DR RefSeq; NP_001072235.1; NM_001078767.1.
DR AlphaFoldDB; Q0VFH9; -.
DR SMR; Q0VFH9; -.
DR STRING; 8364.ENSXETP00000046789; -.
DR DNASU; 779682; -.
DR Ensembl; ENSXETT00000004097; ENSXETP00000004097; ENSXETG00000021651.
DR GeneID; 779682; -.
DR KEGG; xtr:779682; -.
DR CTD; 286183; -.
DR Xenbase; XB-GENE-5816251; nkain3.
DR eggNOG; KOG4556; Eukaryota.
DR InParanoid; Q0VFH9; -.
DR OrthoDB; 1281511at2759; -.
DR Proteomes; UP000008143; Chromosome 6.
DR Proteomes; UP000790000; Unplaced.
DR Bgee; ENSXETG00000021651; Expressed in brain and 4 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002028; P:regulation of sodium ion transport; IBA:GO_Central.
DR InterPro; IPR008516; Na/K-Atpase_Interacting.
DR PANTHER; PTHR13084; PTHR13084; 1.
DR Pfam; PF05640; NKAIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..181
FT /note="Sodium/potassium-transporting ATPase subunit beta-1-
FT interacting protein 3"
FT /id="PRO_0000310470"
FT TRANSMEM 5..22
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 181 AA; 20779 MW; 19791128D564AF8B CRC64;
MGCCTGRCTL IFICTLQMLV ALERQIFDFL GYQWAPILGN FLHIIVVILG LFGTIQYRPR
YIVAYTIWTA FWVAWNVFII CFYLEVGGLS KDTDLMTFNI SIHRSWWREH GPGCVWRLVP
APPSKNLGDH SFISVTGCII EFQYIEVIHS AVQILLSLIG FVYACYVISV ITDEEDSCRH
K