NKAI4_XENTR
ID NKAI4_XENTR Reviewed; 208 AA.
AC Q6DEX3;
DT 13-NOV-2007, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 56.
DE RecName: Full=Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4;
DE Short=Na(+)/K(+)-transporting ATPase subunit beta-1-interacting protein 4;
GN Name=nkain4;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUL-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBUNIT: Interacts with atp1b1 C-terminus. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the NKAIN family. {ECO:0000305}.
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DR EMBL; BC076970; AAH76970.1; -; mRNA.
DR RefSeq; NP_001005067.1; NM_001005067.1.
DR AlphaFoldDB; Q6DEX3; -.
DR SMR; Q6DEX3; -.
DR DNASU; 448628; -.
DR GeneID; 448628; -.
DR KEGG; xtr:448628; -.
DR CTD; 128414; -.
DR Xenbase; XB-GENE-6455573; nkain4.
DR InParanoid; Q6DEX3; -.
DR OrthoDB; 1281511at2759; -.
DR Proteomes; UP000008143; Chromosome 10.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0002028; P:regulation of sodium ion transport; IBA:GO_Central.
DR InterPro; IPR008516; Na/K-Atpase_Interacting.
DR PANTHER; PTHR13084; PTHR13084; 1.
DR Pfam; PF05640; NKAIN; 1.
PE 2: Evidence at transcript level;
KW Cell membrane; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..208
FT /note="Sodium/potassium-transporting ATPase subunit beta-1-
FT interacting protein 4"
FT /id="PRO_0000310472"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 35..55
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 62..82
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 151..171
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 208 AA; 23663 MW; 9715D64DCDAA5E6F CRC64;
MACCTGRCTL ILLCTLQLVA ALERQVFDFL GYQWAPILAN FLHIVATILG LFGTLQYRPR
YVIAYALWAA VWVTWNVFLI CFYLEVGDLN KESELLTFHV SQHQSWWSEH GPGCVRKEAP
VAGVAELESH SYVSVIGCNV EYQYIEVMHS ALQILLALLG FVYACYVTSV FTEEEDSFDF
IGGFDPFPLY HVNEKSNHLL FKQSYLPA