ID   NKAP_DICDI              Reviewed;         510 AA.
AC   Q55ED4;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=NKAP family protein {ECO:0000305};
GN   ORFNames=DDB_G0269284;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- SIMILARITY: Belongs to the NKAP family. {ECO:0000305}.
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DR   EMBL; AAFI02000005; EAL71992.1; -; Genomic_DNA.
DR   RefSeq; XP_645847.1; XM_640755.1.
DR   AlphaFoldDB; Q55ED4; -.
DR   SMR; Q55ED4; -.
DR   STRING; 44689.DDB0190150; -.
DR   PaxDb; Q55ED4; -.
DR   PRIDE; Q55ED4; -.
DR   EnsemblProtists; EAL71992; EAL71992; DDB_G0269284.
DR   GeneID; 8616791; -.
DR   KEGG; ddi:DDB_G0269284; -.
DR   dictyBase; DDB_G0269284; nkaP.
DR   eggNOG; KOG2812; Eukaryota.
DR   HOGENOM; CLU_534667_0_0_1; -.
DR   InParanoid; Q55ED4; -.
DR   OMA; MMPGEAD; -.
DR   PRO; PR:Q55ED4; -.
DR   Proteomes; UP000002195; Chromosome 1.
DR   GO; GO:0005737; C:cytoplasm; IDA:dictyBase.
DR   GO; GO:0005634; C:nucleus; IDA:dictyBase.
DR   GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR   GO; GO:0003729; F:mRNA binding; IDA:dictyBase.
DR   GO; GO:0019843; F:rRNA binding; IDA:dictyBase.
DR   GO; GO:0030515; F:snoRNA binding; IDA:dictyBase.
DR   GO; GO:0017069; F:snRNA binding; IDA:dictyBase.
DR   GO; GO:0010468; P:regulation of gene expression; IMP:dictyBase.
DR   InterPro; IPR040466; NKAP.
DR   InterPro; IPR009269; NKAP_C.
DR   PANTHER; PTHR13087; PTHR13087; 1.
DR   Pfam; PF06047; Nkap_C; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..510
FT                   /note="NKAP family protein"
FT                   /id="PRO_0000372659"
FT   REGION          1..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          149..220
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          239..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..26
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        27..41
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        42..89
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        90..128
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        157..171
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        172..186
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        187..220
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        246..263
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        294..319
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        352..367
FT                   /note="Basic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   510 AA;  59615 MW;  5524B91B70AD1E0A CRC64;
     MSHRERDRDR DRDSDRDRDR NRYSRSRSRG SRSRSRSRSR SRDRNRNRDY NKDRSSNRDS
     YYNDRDYKKD RSSNRDRDYY DRDRNRDYKN SSSGSSSGGG GGGSGENYTV KSSSYRESNS
     NNSKVEIQKQ ENISKDYFID NKGVNNSIER KDNIKNENNN NNSFDNRKAE FNNNSYGEKK
     EFDNNNNRNY HGGNSRYVNN NNNNNNNNYN NNNNKSNYNG TDFFEYRKKL REEATCFSVY
     ERSPSPPKKG ELEEIDDQFL SNKKKSKKSR RKSSSNSDSS SSDSDSDSSR SREKRKKSKS
     RKDKKKRKEK KKHQRKSSKR SSKYSDSDSD SDSSFSDSDY SDSDRSDSEG RSRKKRSKKR
     SKKRHDHHKE SVHDASMWEE KVEQQTQTLS NRDIGPKPIS EVQVGSYGGA MMPGEAEAIA
     QFVKENKRIP RRGEVGLTSE QIASFEETGY VMSGSRHRRM NAVRIRKESQ VYSAEEQKAL
     AMLNREEKAK RENRLLADFR DLINTKLQAD