ID   NLAL2_ARATH             Reviewed;         189 AA.
AC   Q9FK53;
DT   05-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=H/ACA ribonucleoprotein complex subunit 1-like protein 2;
GN   OrderedLocusNames=At5g18180; ORFNames=MRG7.14;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=9734815; DOI=10.1093/dnares/5.3.203;
RA   Kotani H., Nakamura Y., Sato S., Asamizu E., Kaneko T., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VI. Sequence
RT   features of the regions of 1,367,185 bp covered by 19 physically assigned
RT   P1 and TAC clones.";
RL   DNA Res. 5:203-216(1998).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- FUNCTION: Required for ribosome biogenesis. Part of a complex which
CC       catalyzes pseudouridylation of rRNA. This involves the isomerization of
CC       uridine such that the ribose is subsequently attached to C5, instead of
CC       the normal N1. Pseudouridine ('psi') residues may serve to stabilize
CC       the conformation of rRNAs (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the small nucleolar ribonucleoprotein particle
CC       containing H/ACA-type snoRNAs (H/ACA snoRNPs). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the GAR1 family. {ECO:0000305}.
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DR   EMBL; AB012246; BAB09476.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED92516.1; -; Genomic_DNA.
DR   RefSeq; NP_197319.1; NM_121823.2.
DR   AlphaFoldDB; Q9FK53; -.
DR   SMR; Q9FK53; -.
DR   BioGRID; 17212; 2.
DR   STRING; 3702.AT5G18180.1; -.
DR   PaxDb; Q9FK53; -.
DR   PRIDE; Q9FK53; -.
DR   ProteomicsDB; 251062; -.
DR   EnsemblPlants; AT5G18180.1; AT5G18180.1; AT5G18180.
DR   GeneID; 831936; -.
DR   Gramene; AT5G18180.1; AT5G18180.1; AT5G18180.
DR   KEGG; ath:AT5G18180; -.
DR   Araport; AT5G18180; -.
DR   TAIR; locus:2172329; AT5G18180.
DR   eggNOG; KOG3262; Eukaryota.
DR   HOGENOM; CLU_080002_0_0_1; -.
DR   InParanoid; Q9FK53; -.
DR   OMA; NQKRSEV; -.
DR   OrthoDB; 1530008at2759; -.
DR   PhylomeDB; Q9FK53; -.
DR   PRO; PR:Q9FK53; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FK53; baseline and differential.
DR   Genevisible; Q9FK53; AT.
DR   GO; GO:0031429; C:box H/ACA snoRNP complex; IBA:GO_Central.
DR   GO; GO:0009535; C:chloroplast thylakoid membrane; HDA:TAIR.
DR   GO; GO:0034513; F:box H/ACA snoRNA binding; IBA:GO_Central.
DR   GO; GO:0000454; P:snoRNA guided rRNA pseudouridine synthesis; IBA:GO_Central.
DR   Gene3D; 2.40.10.230; -; 1.
DR   InterPro; IPR038664; Gar1/Naf1_Cbf5-bd_sf.
DR   InterPro; IPR007504; H/ACA_rnp_Gar1/Naf1.
DR   InterPro; IPR009000; Transl_B-barrel_sf.
DR   Pfam; PF04410; Gar1; 1.
DR   SUPFAM; SSF50447; SSF50447; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; Repeat; Ribonucleoprotein;
KW   Ribosome biogenesis; RNA-binding; rRNA processing.
FT   CHAIN           1..189
FT                   /note="H/ACA ribonucleoprotein complex subunit 1-like
FT                   protein 2"
FT                   /id="PRO_0000208561"
FT   REGION          1..39
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          129..189
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   189 AA;  20313 MW;  A062B79FA476038A CRC64;
     MRPPRGGGSF RGRGGRDNGG RGRGRGRGRG RFGGGNYDEG PPSEVVEVAT FLHACEGDAV
     FKLSNVKIPH FNAPIYLQNK TQIGRVDEIF GPINESLFSI KMREGIVATS YSQGDKFFIS
     PEKLLPLSRF LPQPKGQSGG RGEGRVPPRG RGPPRGRGNF RGRGAPRGAS RGFQPRGGPR
     GGFRGRGRA