NLP15_PHYCP
ID NLP15_PHYCP Reviewed; 132 AA.
AC L7NCS2;
DT 05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT 03-APR-2013, sequence version 1.
DT 03-AUG-2022, entry version 16.
DE RecName: Full=NLP effector protein 15 {ECO:0000303|PubMed:24886309};
DE AltName: Full=Necrosis-inducing protein 15 {ECO:0000303|PubMed:21644208};
DE AltName: Full=Nep1-like protein 15 {ECO:0000303|PubMed:21644208};
GN Name=NLP15 {ECO:0000303|PubMed:24886309};
GN Synonyms=NPP15 {ECO:0000303|PubMed:21644208};
OS Phytophthora capsici.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=4784;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND DOMAIN.
RX PubMed=21644208; DOI=10.4238/vol10-2gmr1248;
RA Feng B.Z., Li P.Q., Fu L., Sun B.B., Zhang X.G.;
RT "Identification of 18 genes encoding necrosis-inducing proteins from the
RT plant pathogen Phytophthora capsici (Pythiaceae: Oomycetes).";
RL Genet. Mol. Res. 10:910-922(2011).
RN [2]
RP INDUCTION, AND FUNCTION.
RX PubMed=24886309; DOI=10.1186/1471-2229-14-126;
RA Feng B.Z., Zhu X.P., Fu L., Lv R.F., Storey D., Tooley P., Zhang X.G.;
RT "Characterization of necrosis-inducing NLP proteins in Phytophthora
RT capsici.";
RL BMC Plant Biol. 14:126-126(2014).
CC -!- FUNCTION: Secreted effector that contributes moderately to virulence
CC during infection by P.capsici. Causes only small yellow areas at 3 days
CC after inoculation of host C.annuum leaves; these areas expand somewhat
CC and became necrotic at 7 days after inoculation. Leads only to
CC chlorotic areas, without necrosis at 7 days after non-host
CC N.benthamiana leaves infection. {ECO:0000269|PubMed:24886309}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:21644208}.
CC -!- INDUCTION: Expression gradually increases to a maximum at 7 days after
CC inoculation of pepper leaves. {ECO:0000269|PubMed:24886309}.
CC -!- DOMAIN: The structure of NLP effectors is remarkably conserved with a
CC high level of conservation of a central hepta-peptide motif GHRHDWE.
CC {ECO:0000305|PubMed:21644208}.
CC -!- SIMILARITY: Belongs to the Necrosis inducing protein (NPP1) family.
CC {ECO:0000305}.
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DR EMBL; HM543181; AEJ88246.1; -; Genomic_DNA.
DR AlphaFoldDB; L7NCS2; -.
DR SMR; L7NCS2; -.
DR VEuPathDB; FungiDB:DVH05_000857; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR InterPro; IPR008701; NPP1.
DR PANTHER; PTHR33657; PTHR33657; 1.
DR Pfam; PF05630; NPP1; 1.
PE 2: Evidence at transcript level;
KW Secreted; Virulence.
FT CHAIN 1..132
FT /note="NLP effector protein 15"
FT /id="PRO_0000447428"
FT MOTIF 16..22
FT /note="Hepta-peptide GHRHDWE motif"
FT /evidence="ECO:0000305|PubMed:24886309"
SQ SEQUENCE 132 AA; 15095 MW; 08026D2F2F9AF790 CRC64;
MYSWYFPKDS PSTGMGHRHD WEHAIVFIDN PDVPEPKILA CSVSSHAGYK KYNPCPPWVI
DGTSLKVRYK HGWPLNHDLD TTGDAGTFQD LIMWDQMTED ARRALNSVHF GSANTPFNDG
NFKPKLEKAW PF
