NLP1_ARATH
ID NLP1_ARATH Reviewed; 909 AA.
AC Q8H111; Q56XE7;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 25-MAY-2022, entry version 104.
DE RecName: Full=Protein NLP1;
DE Short=AtNLP1;
DE AltName: Full=NIN-like protein 1;
DE AltName: Full=Nodule inception protein-like protein 1;
GN Name=NLP1; OrderedLocusNames=At2g17150; ORFNames=F6P23.15, T23A1;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15785851; DOI=10.1007/s00239-004-0144-2;
RA Schauser L., Wieloch W., Stougaard J.;
RT "Evolution of NIN-like proteins in Arabidopsis, rice, and Lotus
RT japonicus.";
RL J. Mol. Evol. 60:229-237(2005).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00852}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8H111-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8H111-2; Sequence=VSP_040192, VSP_040193, VSP_040194;
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC007127; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC06591.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC06592.1; -; Genomic_DNA.
DR EMBL; CP002685; ANM62251.1; -; Genomic_DNA.
DR EMBL; BT000911; AAN41311.1; -; mRNA.
DR EMBL; AK221727; BAD93733.1; -; mRNA.
DR RefSeq; NP_001031361.2; NM_001036284.3. [Q8H111-2]
DR RefSeq; NP_001324424.1; NM_001335542.1. [Q8H111-1]
DR RefSeq; NP_179306.2; NM_127269.3. [Q8H111-1]
DR AlphaFoldDB; Q8H111; -.
DR SMR; Q8H111; -.
DR BioGRID; 1577; 8.
DR IntAct; Q8H111; 5.
DR STRING; 3702.AT2G17150.1; -.
DR iPTMnet; Q8H111; -.
DR PaxDb; Q8H111; -.
DR PRIDE; Q8H111; -.
DR EnsemblPlants; AT2G17150.1; AT2G17150.1; AT2G17150. [Q8H111-1]
DR EnsemblPlants; AT2G17150.2; AT2G17150.2; AT2G17150. [Q8H111-2]
DR EnsemblPlants; AT2G17150.6; AT2G17150.6; AT2G17150. [Q8H111-1]
DR GeneID; 816220; -.
DR Gramene; AT2G17150.1; AT2G17150.1; AT2G17150. [Q8H111-1]
DR Gramene; AT2G17150.2; AT2G17150.2; AT2G17150. [Q8H111-2]
DR Gramene; AT2G17150.6; AT2G17150.6; AT2G17150. [Q8H111-1]
DR KEGG; ath:AT2G17150; -.
DR Araport; AT2G17150; -.
DR TAIR; locus:2059692; AT2G17150.
DR eggNOG; ENOG502QQ6H; Eukaryota.
DR HOGENOM; CLU_008971_0_0_1; -.
DR InParanoid; Q8H111; -.
DR OMA; RTREDPC; -.
DR OrthoDB; 1337805at2759; -.
DR PhylomeDB; Q8H111; -.
DR PRO; PR:Q8H111; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8H111; baseline and differential.
DR Genevisible; Q8H111; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR CDD; cd06407; PB1_NLP; 1.
DR InterPro; IPR045012; NLP.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR034891; PB1_NLP.
DR InterPro; IPR003035; RWP-RK_dom.
DR PANTHER; PTHR32002; PTHR32002; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF02042; RWP-RK; 1.
DR SMART; SM00666; PB1; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS51519; RWP_RK; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; DNA-binding; Nucleus; Reference proteome;
KW Transcription; Transcription regulation.
FT CHAIN 1..909
FT /note="Protein NLP1"
FT /id="PRO_0000401486"
FT DOMAIN 595..676
FT /note="RWP-RK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00852"
FT DOMAIN 811..894
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT REGION 51..71
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 536..556
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..605
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 690..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 568..592
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 294..297
FT /note="EFLQ -> E (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_040192"
FT VAR_SEQ 631..657
FT /note="VCPTTLKRICRQHGIMRWPSRKIKKVG -> GKRMLYTAGDIAPFFMNFDSY
FT CFLGKA (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_040193"
FT VAR_SEQ 658..909
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|Ref.4"
FT /id="VSP_040194"
SQ SEQUENCE 909 AA; 100886 MW; F8A8AFD3DB0DA470 CRC64;
MEDDGGSDGG EGNGGFSPNS SFGAFADTAM DLDFMDELLF DGCWLETTDS KSLKQTEQSP
SASTAMNDNS PFLCFGENPS QDNFSNEETE RMFPQAEKFL LEEAEVGKSW WIAPSASEGP
SSSVKERLLQ AISGLNEAVQ DKDFLVQIWV PIQQEGKSFL TTWAQPHLFN QEYSSLAEYR
HVSETYNFPA DEGMKDFVGL PGRVFLQKFP EWTPDVRFFR RDEYPRIKEA QKCDVRGSLA
LPVFERGSGT CLGVVEIVTT TQKMNYRQEL EKMCKALEAV DLRSSSNLNT PSSEFLQVYS
DFYCAALPEI KDFLATICRS YDFPLALSWA PCARQGKVGS RHSDENFSEC VSTIDSACSV
PDEQSKSFWE ACSEHHLLQG EGIVGKAFEA TKLFFVPEVA TFSKTNYPLA HHAKISGLHA
ALAVPLKSKS GLVEFVLEFF FPKACLDTEA QQEMLKSLCV TLQQDFRSSN LFIKDLELEV
VLPVRETMLF SENLLCGAET VESLTEIQMQ ESSWIAHMIK ANEKGKDVSL SWEYQKEDPK
ELSSGRENSQ LDPVPNNVPL EAEQLQQAST PGLRVDIGPS TESASTGGGN MLSSRRPGEK
KRAKTEKTIG LEVLRQYFAG SLKDAAKSIG VCPTTLKRIC RQHGIMRWPS RKIKKVGHSL
KKLQLVMDSV QGAQGSIQLD SFYTSFPELN SPNMSSNGPS LKSNEQPSHL NAQTDNGIMA
EENPRSPSSS CSKSSGSSNN NENTGNILVA EDADAVLKRA HSEAQLHNVN QEETKCLART
QSHKTFKEPL VLDNSSPLTG SSNTSLRARG AIKVKATFGE ARIRFTLLPS WGFAELKQEI
ARRFNIDDIS WFDLKYLDDD KEWVLLTCEA DLVECIDIYR LTQTHTIKIS LNEASQVKLS
GSFGNTGLS
