ID   NLP1_CAEEL              Reviewed;         176 AA.
AC   Q11088;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   27-MAY-2002, sequence version 2.
DT   03-AUG-2022, entry version 86.
DE   RecName: Full=Neuropeptide-like protein 1;
DE   Flags: Precursor;
GN   Name=nlp-1; ORFNames=C01C4.1;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   FUNCTION, AND DISRUPTION PHENOTYPE.
RX   PubMed=25009271; DOI=10.1523/jneurosci.0012-14.2014;
RA   Harris G., Shen Y., Ha H., Donato A., Wallis S., Zhang X., Zhang Y.;
RT   "Dissecting the signaling mechanisms underlying recognition and preference
RT   of food odors.";
RL   J. Neurosci. 34:9389-9403(2014).
CC   -!- FUNCTION: In AWC olfactory sensory neurons, required for the detection
CC       of preferred food sources. {ECO:0000269|PubMed:25009271}.
CC   -!- DISRUPTION PHENOTYPE: Defective preference between different food
CC       odors. {ECO:0000269|PubMed:25009271}.
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DR   EMBL; FO080252; CCD62363.1; -; Genomic_DNA.
DR   PIR; T34076; T34076.
DR   RefSeq; NP_508640.1; NM_076239.4.
DR   AlphaFoldDB; Q11088; -.
DR   BioGRID; 45599; 1.
DR   IntAct; Q11088; 1.
DR   STRING; 6239.C01C4.1; -.
DR   PaxDb; Q11088; -.
DR   EnsemblMetazoa; C01C4.1.1; C01C4.1.1; WBGene00003739.
DR   GeneID; 180661; -.
DR   KEGG; cel:CELE_C01C4.1; -.
DR   UCSC; C01C4.1; c. elegans.
DR   CTD; 180661; -.
DR   WormBase; C01C4.1; CE29554; WBGene00003739; nlp-1.
DR   eggNOG; ENOG502THJB; Eukaryota.
DR   HOGENOM; CLU_1564300_0_0_1; -.
DR   InParanoid; Q11088; -.
DR   OMA; RMDPNAF; -.
DR   OrthoDB; 1469335at2759; -.
DR   PRO; PR:Q11088; -.
DR   Proteomes; UP000001940; Chromosome X.
DR   Bgee; WBGene00003739; Expressed in larva and 3 other tissues.
DR   GO; GO:0071244; P:cellular response to carbon dioxide; IMP:UniProtKB.
DR   GO; GO:1903745; P:negative regulation of pharyngeal pumping; IMP:UniProtKB.
DR   GO; GO:0001966; P:thigmotaxis; IMP:WormBase.
PE   3: Inferred from homology;
KW   Reference proteome; Signal.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..176
FT                   /note="Neuropeptide-like protein 1"
FT                   /id="PRO_0000014274"
FT   REGION          59..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        65..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   176 AA;  20081 MW;  EF58809D2034267C CRC64;
     MKATFVLACL LVIAAVSHAD LLPKRMDANA FRMSFGKRSV SNPAEAKRMD PNAFRMSFGK
     RSAEQNEQAN KEDKATSDKL YDDTKFEEMK RMDANAFRMS FGKRSDAHQA ADDQVEYVND
     DFSLPEQKRM DANAFRMSFG KRVNLDPNSF RMSFGKRSTV GYNLDARNYF VGLGRR