NLP8_ARATH
ID NLP8_ARATH Reviewed; 947 AA.
AC O22864; Q8L4P4;
DT 30-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 03-AUG-2022, entry version 116.
DE RecName: Full=Protein NLP8;
DE Short=AtNLP8;
DE AltName: Full=NIN-like protein 8;
DE AltName: Full=Nodule inception protein-like protein 8;
GN Name=NLP8; OrderedLocusNames=At2g43500; ORFNames=T1O24.24;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC STRAIN=cv. Columbia;
RX PubMed=16244158; DOI=10.1104/pp.105.063479;
RA Xiao Y.-L., Smith S.R., Ishmael N., Redman J.C., Kumar N., Monaghan E.L.,
RA Ayele M., Haas B.J., Wu H.C., Town C.D.;
RT "Analysis of the cDNAs of hypothetical genes on Arabidopsis chromosome 2
RT reveals numerous transcript variants.";
RL Plant Physiol. 139:1323-1337(2005).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=15785851; DOI=10.1007/s00239-004-0144-2;
RA Schauser L., Wieloch W., Stougaard J.;
RT "Evolution of NIN-like proteins in Arabidopsis, rice, and Lotus
RT japonicus.";
RL J. Mol. Evol. 60:229-237(2005).
CC -!- FUNCTION: Probable transcription factor. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00852}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=O22864-1; Sequence=Displayed;
CC Name=2;
CC IsoId=O22864-2; Sequence=VSP_040195, VSP_040196;
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DR EMBL; AC002335; AAB64326.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC10283.1; -; Genomic_DNA.
DR EMBL; AY649251; AAT69168.1; -; Genomic_DNA.
DR EMBL; AY102562; AAM76767.1; -; mRNA.
DR EMBL; AY102563; AAM76768.1; -; mRNA.
DR PIR; H84866; H84866.
DR RefSeq; NP_001154573.1; NM_001161101.2. [O22864-1]
DR AlphaFoldDB; O22864; -.
DR SMR; O22864; -.
DR STRING; 3702.AT2G43500.2; -.
DR PaxDb; O22864; -.
DR PRIDE; O22864; -.
DR ProteomicsDB; 250536; -. [O22864-1]
DR EnsemblPlants; AT2G43500.2; AT2G43500.2; AT2G43500. [O22864-1]
DR GeneID; 818951; -.
DR Gramene; AT2G43500.2; AT2G43500.2; AT2G43500. [O22864-1]
DR KEGG; ath:AT2G43500; -.
DR Araport; AT2G43500; -.
DR TAIR; locus:2058244; AT2G43500.
DR eggNOG; ENOG502QQ6H; Eukaryota.
DR HOGENOM; CLU_008971_0_0_1; -.
DR InParanoid; O22864; -.
DR PhylomeDB; O22864; -.
DR PRO; PR:O22864; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22864; baseline and differential.
DR Genevisible; O22864; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR CDD; cd06407; PB1_NLP; 1.
DR InterPro; IPR045012; NLP.
DR InterPro; IPR000270; PB1_dom.
DR InterPro; IPR034891; PB1_NLP.
DR InterPro; IPR003035; RWP-RK_dom.
DR PANTHER; PTHR32002; PTHR32002; 1.
DR Pfam; PF00564; PB1; 1.
DR Pfam; PF02042; RWP-RK; 1.
DR SMART; SM00666; PB1; 1.
DR PROSITE; PS51745; PB1; 1.
DR PROSITE; PS51519; RWP_RK; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Coiled coil; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..947
FT /note="Protein NLP8"
FT /id="PRO_0000401493"
FT DOMAIN 577..671
FT /note="RWP-RK"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00852"
FT DOMAIN 847..929
FT /note="PB1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01081"
FT REGION 114..135
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..533
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 550..591
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 805..828
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 646..666
FT /evidence="ECO:0000255"
FT COMPBIAS 519..533
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 550..574
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 316..348
FT /note="AVNLRTAAIPRPQYLSSSQRDALAEIQDVLRTV -> VDTLFSPSLSFCFVL
FT FFCLYVCLRVLLSPARLL (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16244158"
FT /id="VSP_040195"
FT VAR_SEQ 349..947
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:16244158"
FT /id="VSP_040196"
SQ SEQUENCE 947 AA; 104884 MW; 158218E64E17CD69 CRC64;
MENPFASREK GFGNYSDFPT EQMDGLSSNF GSGVRNLISD DMFNPSSELM NFDSLAAWCN
SPSATDILFA QYGLSNSQPM PFGAFTSFHV ADPKATSLTR SFYDLESSYY GEERSSAQEM
NSQFHRSSDS DELSGKRRKV VNQKIGFPNV LNCTIPRSLS HSLDEKMLKA LSLFMESSGS
GEGILAQVWT PIKTGDQYLL STCDQAYLLD PRFSQYREVS RRFTFAAEAN QCSFPGLPGR
VFISGVPEWT SNVMYYKTDE YLRMKHAIDN EVRGSIAIPI LEASGTSCCA VMELVTSKEK
PNFDMEMDSV CRALQAVNLR TAAIPRPQYL SSSQRDALAE IQDVLRTVCH AHKLPLALAW
IPCRKDQSIR VSGQKSGENC ILCIEETACY VNDMEMEGFV HACLEHCLRE KEGIVGKAFI
SNQPFFSSDV KAYDISEYPI VQHARKYGLN AAVAIKLRST YTGEDDYILE LFLPVSMKGS
LEQQLLLDSL SGTMQRICRT LRTVSEVGST KKEGTKPGFR SSDMSNFPQT TSSENFQTIS
LDSEFNSTRS MFSGMSSDKE NSITVSQGTL EQDVSKARTP EKKKSTTEKN VSLSALQQHF
SGSLKDAAKS LGGETSAYFQ AWVYFFCPTT LKRICRQHGI MRWPSRKINK VNRSLRKIQT
VLDSVQGVEG GLKFDSATGE FIAVRPFIQE IDTQKGLSSL DNDAHARRSQ EDMPDDTSFK
LQEAKSVDNA IKLEEDTTMN QARPGSFMEV NASGQPWAWM AKESGLNGSE GIKSVCNLSS
VEISDGMDPT IRCSGSIVEP NQSMSCSISD SSNGSGAVLR GSSSTSMEDW NQMRTHNSNS
SESGSTTLIV KASYREDTVR FKFEPSVGCP QLYKEVGKRF KLQDGSFQLK YLDDEEEWVM
LVTDSDLQEC LEILHGMGKH SVKFLVRDLS APLGSSGGSN GYLGTGL
