NLTP1_ARATH
ID NLTP1_ARATH Reviewed; 118 AA.
AC Q42589;
DT 01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 145.
DE RecName: Full=Non-specific lipid-transfer protein 1;
DE Short=LTP 1;
DE Flags: Precursor;
GN Name=LTP1; OrderedLocusNames=At2g38540; ORFNames=T6A23.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Shoot;
RX PubMed=8029357; DOI=10.1104/pp.105.1.35;
RA Thoma S., Hecht U., Kippers A., Botella J., de Vries S., Somerville C.R.;
RT "Tissue-specific expression of a gene encoding a cell wall-localized lipid
RT transfer protein from Arabidopsis.";
RL Plant Physiol. 105:35-45(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=10940464; DOI=10.1016/s0168-9452(00)00232-6;
RA Arondel V.A., Vergnolle C., Cantrel C., Kader J.-C.;
RT "Lipid transfer proteins are encoded by a small multigene family in
RT Arabidopsis thaliana.";
RL Plant Sci. 157:1-12(2000).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP SUBCELLULAR LOCATION.
RX PubMed=8220451; DOI=10.1046/j.1365-313x.1993.t01-25-00999.x;
RA Thoma S., Kaneko Y., Somerville C.R.;
RT "A non-specific lipid transfer protein from Arabidopsis is a cell wall
RT protein.";
RL Plant J. 3:427-436(1993).
RN [7]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=18674922; DOI=10.1016/j.plaphy.2008.06.011;
RA Sels J., Mathys J., De Coninck B.M.A., Cammue B.P.A., De Bolle M.F.C.;
RT "Plant pathogenesis-related (PR) proteins: a focus on PR peptides.";
RL Plant Physiol. Biochem. 46:941-950(2008).
CC -!- FUNCTION: Plant non-specific lipid-transfer proteins transfer
CC phospholipids as well as galactolipids across membranes. May play a
CC role in wax or cutin deposition in the cell walls of expanding
CC epidermal cells and certain secretory tissues.
CC -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000269|PubMed:8220451}.
CC -!- TISSUE SPECIFICITY: Expressed primarily in epidermal cells.
CC -!- SIMILARITY: Belongs to the plant LTP family. {ECO:0000305}.
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DR EMBL; M80567; AAA86765.1; -; Genomic_DNA.
DR EMBL; AF159798; AAF76927.1; -; mRNA.
DR EMBL; AC005499; AAC67364.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC09547.1; -; Genomic_DNA.
DR EMBL; AY049296; AAK83638.1; -; mRNA.
DR EMBL; AY091677; AAM10276.1; -; mRNA.
DR PIR; C84806; C84806.
DR RefSeq; NP_181388.1; NM_129411.4.
DR AlphaFoldDB; Q42589; -.
DR SMR; Q42589; -.
DR BioGRID; 3778; 2.
DR MINT; Q42589; -.
DR STRING; 3702.AT2G38540.1; -.
DR Allergome; 1085; Ara t 3.
DR PaxDb; Q42589; -.
DR PRIDE; Q42589; -.
DR ProteomicsDB; 251139; -.
DR EnsemblPlants; AT2G38540.1; AT2G38540.1; AT2G38540.
DR GeneID; 818436; -.
DR Gramene; AT2G38540.1; AT2G38540.1; AT2G38540.
DR KEGG; ath:AT2G38540; -.
DR Araport; AT2G38540; -.
DR TAIR; locus:2064212; AT2G38540.
DR eggNOG; ENOG502S4CI; Eukaryota.
DR HOGENOM; CLU_128423_0_0_1; -.
DR InParanoid; Q42589; -.
DR OMA; IPANCCG; -.
DR OrthoDB; 1546493at2759; -.
DR PhylomeDB; Q42589; -.
DR PRO; PR:Q42589; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q42589; baseline and differential.
DR Genevisible; Q42589; AT.
DR GO; GO:0048046; C:apoplast; HDA:TAIR.
DR GO; GO:0009534; C:chloroplast thylakoid; HDA:TAIR.
DR GO; GO:0005794; C:Golgi apparatus; HDA:TAIR.
DR GO; GO:0009505; C:plant-type cell wall; IDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0099503; C:secretory vesicle; HDA:TAIR.
DR GO; GO:0005516; F:calmodulin binding; IDA:TAIR.
DR GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0006869; P:lipid transport; TAS:TAIR.
DR Gene3D; 1.10.110.10; -; 1.
DR InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR InterPro; IPR000528; Plant_nsLTP.
DR PANTHER; PTHR33076; PTHR33076; 1.
DR Pfam; PF00234; Tryp_alpha_amyl; 1.
DR PRINTS; PR00382; LIPIDTRNSFER.
DR SMART; SM00499; AAI; 1.
DR SUPFAM; SSF47699; SSF47699; 1.
DR PROSITE; PS00597; PLANT_LTP; 1.
PE 2: Evidence at transcript level;
KW Cell wall; Cell wall biogenesis/degradation; Disulfide bond; Lipid-binding;
KW Reference proteome; Secreted; Signal; Transport.
FT SIGNAL 1..25
FT /evidence="ECO:0000255"
FT CHAIN 26..118
FT /note="Non-specific lipid-transfer protein 1"
FT /id="PRO_0000018361"
FT DISULFID 29..76
FT /evidence="ECO:0000255"
FT DISULFID 39..53
FT /evidence="ECO:0000255"
FT DISULFID 54..100
FT /evidence="ECO:0000255"
FT DISULFID 74..114
FT /evidence="ECO:0000255"
SQ SEQUENCE 118 AA; 11755 MW; AED716F6FDB6B33E CRC64;
MAGVMKLACL LLACMIVAGP ITSNAALSCG SVNSNLAACI GYVLQGGVIP PACCSGVKNL
NSIAKTTPDR QQACNCIQGA ARALGSGLNA GRAAGIPKAC GVNIPYKIST STNCKTVR
