ID   NLTP3_ARATH             Reviewed;         115 AA.
AC   Q9LLR7; Q8L9A3; Q9FIE6;
DT   23-MAY-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 123.
DE   RecName: Full=Non-specific lipid-transfer protein 3;
DE            Short=LTP 3;
DE   Flags: Precursor;
GN   Name=LTP3; OrderedLocusNames=At5g59320; ORFNames=MNC17.23;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10940464; DOI=10.1016/s0168-9452(00)00232-6;
RA   Arondel V.A., Vergnolle C., Cantrel C., Kader J.-C.;
RT   "Lipid transfer proteins are encoded by a small multigene family in
RT   Arabidopsis thaliana.";
RL   Plant Sci. 157:1-12(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Stracke R., Palme K.;
RT   "Signal peptide selection derived cDNAs from Arabidopsis thaliana leaves
RT   and guard cells.";
RL   Submitted (AUG-1998) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10048488; DOI=10.1093/dnares/5.6.379;
RA   Asamizu E., Sato S., Kaneko T., Nakamura Y., Kotani H., Miyajima N.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. VIII. Sequence
RT   features of the regions of 1,081,958 bp covered by seventeen physically
RT   assigned P1 and TAC clones.";
RL   DNA Res. 5:379-391(1998).
RN   [4]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [7]
RP   GENE FAMILY, AND NOMENCLATURE.
RX   PubMed=18674922; DOI=10.1016/j.plaphy.2008.06.011;
RA   Sels J., Mathys J., De Coninck B.M.A., Cammue B.P.A., De Bolle M.F.C.;
RT   "Plant pathogenesis-related (PR) proteins: a focus on PR peptides.";
RL   Plant Physiol. Biochem. 46:941-950(2008).
CC   -!- FUNCTION: Plant non-specific lipid-transfer proteins transfer
CC       phospholipids as well as galactolipids across membranes. May play a
CC       role in wax or cutin deposition in the cell walls of expanding
CC       epidermal cells and certain secretory tissues (By similarity).
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the plant LTP family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=BAB09777.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AF159800; AAF76929.1; -; mRNA.
DR   EMBL; AF083697; AAN60256.1; -; mRNA.
DR   EMBL; AB016890; BAB09777.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002688; AED97171.1; -; Genomic_DNA.
DR   EMBL; AY065293; AAL38769.1; -; mRNA.
DR   EMBL; AY094428; AAM19801.1; -; mRNA.
DR   EMBL; AY096572; AAM20222.1; -; mRNA.
DR   EMBL; AY088556; AAM66088.1; -; mRNA.
DR   RefSeq; NP_568905.1; NM_125323.5.
DR   AlphaFoldDB; Q9LLR7; -.
DR   SMR; Q9LLR7; -.
DR   BioGRID; 21295; 2.
DR   STRING; 3702.AT5G59320.1; -.
DR   PaxDb; Q9LLR7; -.
DR   PRIDE; Q9LLR7; -.
DR   ProteomicsDB; 249120; -.
DR   EnsemblPlants; AT5G59320.1; AT5G59320.1; AT5G59320.
DR   GeneID; 836051; -.
DR   Gramene; AT5G59320.1; AT5G59320.1; AT5G59320.
DR   KEGG; ath:AT5G59320; -.
DR   Araport; AT5G59320; -.
DR   TAIR; locus:2168474; AT5G59320.
DR   eggNOG; ENOG502SAKZ; Eukaryota.
DR   HOGENOM; CLU_128423_0_0_1; -.
DR   OMA; CRCIQST; -.
DR   OrthoDB; 1546493at2759; -.
DR   PhylomeDB; Q9LLR7; -.
DR   PRO; PR:Q9LLR7; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9LLR7; baseline and differential.
DR   Genevisible; Q9LLR7; AT.
DR   GO; GO:0048046; C:apoplast; HDA:TAIR.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   GO; GO:0009737; P:response to abscisic acid; IEP:TAIR.
DR   GO; GO:0009414; P:response to water deprivation; IEP:TAIR.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR000528; Plant_nsLTP.
DR   PANTHER; PTHR33076; PTHR33076; 1.
DR   Pfam; PF00234; Tryp_alpha_amyl; 1.
DR   PRINTS; PR00382; LIPIDTRNSFER.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
DR   PROSITE; PS00597; PLANT_LTP; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Lipid-binding; Reference proteome; Signal; Transport.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000255"
FT   CHAIN           24..115
FT                   /note="Non-specific lipid-transfer protein 3"
FT                   /id="PRO_0000018363"
FT   DISULFID        27..74
FT                   /evidence="ECO:0000255"
FT   DISULFID        37..51
FT                   /evidence="ECO:0000255"
FT   DISULFID        52..97
FT                   /evidence="ECO:0000255"
FT   DISULFID        72..111
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   115 AA;  11694 MW;  9D91F7C4D582D105 CRC64;
     MAFALRFFTC LVLTVCIVAS VDAAISCGTV AGSLAPCATY LSKGGLVPPS CCAGVKTLNS
     MAKTTPDRQQ ACRCIQSTAK SISGLNPSLA SGLPGKCGVS IPYPISMSTN CNNIK