ID   NLTP_PYRCO              Reviewed;         115 AA.
AC   Q9M5X6;
DT   20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 66.
DE   RecName: Full=Non-specific lipid-transfer protein;
DE            Short=LTP;
DE   AltName: Allergen=Pyr c 3;
DE   Flags: Precursor;
OS   Pyrus communis (Pear) (Pyrus domestica).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Rosales; Rosaceae; Amygdaloideae; Maleae; Pyrus.
OX   NCBI_TaxID=23211;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RA   Scheurer S., Wangorsch A., Haustein D., Vieths S.;
RT   "Cloning of a cDNA encoding a lipid transfer protein as a potential
RT   allergen from Pyrus communis.";
RL   Submitted (JAN-2000) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plant non-specific lipid-transfer proteins transfer
CC       phospholipids as well as galactolipids across membranes. May play a
CC       role in wax or cutin deposition in the cell walls of expanding
CC       epidermal cells and certain secretory tissues (By similarity).
CC       {ECO:0000250}.
CC   -!- ALLERGEN: Causes an allergic reaction in human.
CC   -!- SIMILARITY: Belongs to the plant LTP family. {ECO:0000305}.
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DR   EMBL; AF221503; AAF26451.1; -; mRNA.
DR   AlphaFoldDB; Q9M5X6; -.
DR   SMR; Q9M5X6; -.
DR   Allergome; 1066; Pyr c 3.
DR   Allergome; 3458; Pyr c 3.0101.
DR   GO; GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:InterPro.
DR   Gene3D; 1.10.110.10; -; 1.
DR   InterPro; IPR036312; Bifun_inhib/LTP/seed_sf.
DR   InterPro; IPR016140; Bifunc_inhib/LTP/seed_store.
DR   InterPro; IPR000528; Plant_nsLTP.
DR   PANTHER; PTHR33076; PTHR33076; 1.
DR   Pfam; PF00234; Tryp_alpha_amyl; 1.
DR   PRINTS; PR00382; LIPIDTRNSFER.
DR   SMART; SM00499; AAI; 1.
DR   SUPFAM; SSF47699; SSF47699; 1.
DR   PROSITE; PS00597; PLANT_LTP; 1.
PE   1: Evidence at protein level;
KW   Allergen; Disulfide bond; Lipid-binding; Signal; Transport.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..115
FT                   /note="Non-specific lipid-transfer protein"
FT                   /id="PRO_0000018404"
FT   DISULFID        27..74
FT                   /evidence="ECO:0000250"
FT   DISULFID        37..51
FT                   /evidence="ECO:0000250"
FT   DISULFID        52..97
FT                   /evidence="ECO:0000250"
FT   DISULFID        72..111
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   115 AA;  11463 MW;  90543BD036AA8D65 CRC64;
     MASSAVIKLA LVVALCMAVS VAHAITCSQV SANLAPCINY VRSGGAVPPA CCNGIKTING
     LAKTTPDRQA ACNCLKNLAG SVSGVNPGNA ESLPGKCGVN VPYKISTSTN CATVK