NMD3_SCHPO
ID NMD3_SCHPO Reviewed; 498 AA.
AC Q09817;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=60S ribosomal export protein nmd3;
GN Name=nmd3; ORFNames=SPAC16C9.03;
OS Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC Schizosaccharomyces.
OX NCBI_TaxID=284812;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=972 / ATCC 24843;
RX PubMed=11859360; DOI=10.1038/nature724;
RA Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA Nurse P.;
RT "The genome sequence of Schizosaccharomyces pombe.";
RL Nature 415:871-880(2002).
CC -!- FUNCTION: Acts as an adapter for the XPO1/CRM1-mediated export of the
CC 60S ribosomal subunit. {ECO:0000250}.
CC -!- SUBUNIT: Associates with the 60S ribosomal subunit. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus, nucleoplasm
CC {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm in a
CC XPO1/CRM1-dependent manner. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the NMD3 family. {ECO:0000305}.
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DR EMBL; CU329670; CAA91191.1; -; Genomic_DNA.
DR PIR; S62473; S62473.
DR RefSeq; NP_593077.1; NM_001018474.2.
DR AlphaFoldDB; Q09817; -.
DR SMR; Q09817; -.
DR BioGRID; 278785; 1.
DR STRING; 4896.SPAC16C9.03.1; -.
DR MaxQB; Q09817; -.
DR PaxDb; Q09817; -.
DR EnsemblFungi; SPAC16C9.03.1; SPAC16C9.03.1:pep; SPAC16C9.03.
DR GeneID; 2542319; -.
DR KEGG; spo:SPAC16C9.03; -.
DR PomBase; SPAC16C9.03; nmd3.
DR VEuPathDB; FungiDB:SPAC16C9.03; -.
DR eggNOG; KOG2613; Eukaryota.
DR HOGENOM; CLU_027444_2_0_1; -.
DR InParanoid; Q09817; -.
DR OMA; ILVKKHY; -.
DR PhylomeDB; Q09817; -.
DR PRO; PR:Q09817; -.
DR Proteomes; UP000002485; Chromosome I.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0005829; C:cytosol; HDA:PomBase.
DR GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; HDA:PomBase.
DR GO; GO:0030674; F:protein-macromolecule adaptor activity; ISS:PomBase.
DR GO; GO:0043023; F:ribosomal large subunit binding; IBA:GO_Central.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR InterPro; IPR039768; Nmd3.
DR InterPro; IPR007064; Nmd3_N.
DR PANTHER; PTHR12746; PTHR12746; 1.
DR Pfam; PF04981; NMD3; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport.
FT CHAIN 1..498
FT /note="60S ribosomal export protein nmd3"
FT /id="PRO_0000116414"
SQ SEQUENCE 498 AA; 56551 MW; 2864C451920FAFE0 CRC64;
MDMDSGSMGV AFQPSEPIAS TILCCECGVP TPPNAAAMCM DCIKMTTDIT SGIPRESTVN
HCRECERYMQ PPNNWMIAPL ESRELMAICL KKLRGLNQVR LVDANFIWTE PHSRRIKVKL
TVQKEAFTNT ILQQSFQVEF YVNNTQCPDC ARTYTPHIWK AVCQVRQKVL HKRTFLYLEQ
IILKHKAHMN TVNIKETKDG IDFYFGQRAH AIKMVEFLSA VVPIRYKGSE ELISEDFKSN
TANYKFTYSI EIVPICKDDL VCLPKTVAKA HGNIAQLVVC TKVGPTIRFL DPLTLQTCDM
LPSIYWRTPF PALADIPELT EFIVADVDLL GPTNGKYALA DVELIKSSDG STHLTRTHLG
GILNAGNTVL AYHLAVTNFN NEVYDTLRED SIPEVVIVKK TYPQTKKKNR NWRLKTIGMQ
KAEDVKKQDI ERQERDYELF LQNLEEDPEL RQGVNLYKAP VKAIAVADTD MDEEDEVDED
IPQISVDELL DDVEAMHI