ID   NMD3_XENLA              Reviewed;         504 AA.
AC   Q6GNS3;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 53.
DE   RecName: Full=60S ribosomal export protein NMD3;
GN   Name=nmd3; Synonyms=nmd3l;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as an adapter for the XPO1/CRM1-mediated export of the
CC       60S ribosomal subunit. {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SUBUNIT: Associates with pre-60S ribosomal particles.
CC       {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96D46}. Nucleus
CC       {ECO:0000250|UniProtKB:Q96D46}. Note=Shuttles between the
CC       nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
CC       {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SIMILARITY: Belongs to the NMD3 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC073430; AAH73430.1; -; mRNA.
DR   RefSeq; NP_001085853.1; NM_001092384.1.
DR   AlphaFoldDB; Q6GNS3; -.
DR   SMR; Q6GNS3; -.
DR   BioGRID; 102443; 1.
DR   IntAct; Q6GNS3; 1.
DR   DNASU; 444280; -.
DR   GeneID; 444280; -.
DR   KEGG; xla:444280; -.
DR   CTD; 444280; -.
DR   Xenbase; XB-GENE-942235; nmd3.L.
DR   OMA; ILVKKHY; -.
DR   OrthoDB; 734666at2759; -.
DR   Proteomes; UP000186698; Chromosome 5L.
DR   Bgee; 444280; Expressed in ovary and 19 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR039768; Nmd3.
DR   InterPro; IPR007064; Nmd3_N.
DR   PANTHER; PTHR12746; PTHR12746; 1.
DR   Pfam; PF04981; NMD3; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..504
FT                   /note="60S ribosomal export protein NMD3"
FT                   /id="PRO_0000323565"
SQ   SEQUENCE   504 AA;  58098 MW;  9908EE4A63663C2E CRC64;
     MEYMKGPATS SQGNILCCQC GIPIPPNPAN MCVACLRTQV DISEGIPKQV SVHFCKQCER
     YLQPPGTWIQ CALESRELLT LCLKKLKANL SKVRLIDAGF IWTEPHSKRL KVKLTIQKEV
     MNGAILQQVF VVDYVVQAQM CDDCHRVEAK DFWKAVVQVR QKVLHKKTFY YLEQTILKHR
     LHQNTLRVKE IHDGLDFYYA SKQHGQKMVE FLQCTVPCRF KASQRLISHD IHTNAYNYKS
     TFSVEIVPVC KDNLVCLSPK LAQSLGNMNQ ICICARVTST IHLIDPSTLQ IAEVDGNTYW
     RYPFNSLFHP KQMEEFIVMD TEIIRDRKQA AGAGMRSNKH VLAEVWVQKT SEMNTTQQYH
     CRTHLGHLLN PGDLVLGFDL SNCNLNDEFI NKMNPHHIPD VVLIKKSYDR ARRQRRRNWK
     LKEMDRDREG MDTDDERQYQ DFLEDLEEDE LLRKNVNIFK NANVPVESDT DEEGAPRISL
     AEMLEDLHIS QDATGEEGAG MLTE