ID   NMD3_XENTR              Reviewed;         504 AA.
AC   Q6P2Z6; Q28FK1;
DT   18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 63.
DE   RecName: Full=60S ribosomal export protein NMD3;
GN   Name=nmd3; Synonyms=nmd3l; ORFNames=TNeu059f02.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Neurula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Acts as an adapter for the XPO1/CRM1-mediated export of the
CC       60S ribosomal subunit. {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SUBUNIT: Associates with pre-60S ribosomal particles.
CC       {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:Q96D46}. Nucleus
CC       {ECO:0000250|UniProtKB:Q96D46}. Note=Shuttles between the
CC       nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.
CC       {ECO:0000250|UniProtKB:Q96D46}.
CC   -!- SIMILARITY: Belongs to the NMD3 family. {ECO:0000305}.
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DR   EMBL; CR761933; CAJ82727.1; -; mRNA.
DR   EMBL; BC064238; AAH64238.1; -; mRNA.
DR   EMBL; BC081303; AAH81303.1; -; mRNA.
DR   RefSeq; NP_989367.2; NM_204036.2.
DR   AlphaFoldDB; Q6P2Z6; -.
DR   SMR; Q6P2Z6; -.
DR   STRING; 8364.ENSXETP00000057710; -.
DR   PaxDb; Q6P2Z6; -.
DR   DNASU; 394998; -.
DR   GeneID; 394998; -.
DR   KEGG; xtr:394998; -.
DR   CTD; 51068; -.
DR   Xenbase; XB-GENE-942228; nmd3.
DR   eggNOG; KOG2613; Eukaryota.
DR   InParanoid; Q6P2Z6; -.
DR   OrthoDB; 734666at2759; -.
DR   Proteomes; UP000008143; Chromosome 5.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0043023; F:ribosomal large subunit binding; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   GO; GO:0000055; P:ribosomal large subunit export from nucleus; IBA:GO_Central.
DR   InterPro; IPR039768; Nmd3.
DR   InterPro; IPR007064; Nmd3_N.
DR   PANTHER; PTHR12746; PTHR12746; 1.
DR   Pfam; PF04981; NMD3; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Protein transport; Reference proteome; Transport.
FT   CHAIN           1..504
FT                   /note="60S ribosomal export protein NMD3"
FT                   /id="PRO_0000323566"
FT   CONFLICT        381
FT                   /note="A -> V (in Ref. 1; CAJ82727)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        491
FT                   /note="L -> Q (in Ref. 1; CAJ82727)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   504 AA;  58091 MW;  C55D1015A6690668 CRC64;
     MEYMKGPATS SQGNILCCQC GIPIPPNPAN MCVSCLRMQV DISEGIPKQV SVHFCKQCER
     YLQPPGTWIQ CALESRELLT LCLKKLKANL SKVRLIDAGF IWTEPHSKRL KVKLTIQKEV
     MNGAILQQVF VVDYIVQSQM CDDCHRVEAK DFWKAVVQVR QKVLHKKTFY YLEQTILKHR
     LHQNTLRVKE IHDGLDFYYA SKQHAQKMVE FLQCTVPCRF KASQRLISHD IHTNAYNYKS
     TFSVEIVPVC KDNLVCLSPK LAQSLGNMNQ ICICVRVTST IHLIDPSTLQ IAEVDGNTYW
     RSPFNSLFHP KQLEEFIVMD TDIVRDRKQA AGAGMRSNKH ILAEVWVQKT SEMNTTQQYH
     CRTHLGHLLN PGDLVLGFDL ANCNLNDEFI NKMNPHHIPD VVLIKKSYDR TKRQRRRNWK
     LKEIERDREG MDTDDERQYQ DFLEDLEEDE VIRKNVNIYK NANLPVESDT DEEGAPRISL
     AEMLEDLHIS LDATGGEGAE MLTE