ID   NMD4_CANGA              Reviewed;         244 AA.
AC   Q6FT66;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Nonsense-mediated decay protein 4;
GN   Name=NMD4; OrderedLocusNames=CAGL0G05005g;
OS   Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL
OS   Y-65) (Yeast) (Torulopsis glabrata).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Nakaseomyces;
OC   Nakaseomyces/Candida clade.
OX   NCBI_TaxID=284593;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in nonsense-mediated decay of mRNAs containing
CC       premature stop codons. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
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DR   EMBL; CR380953; CAG59505.1; -; Genomic_DNA.
DR   RefSeq; XP_446578.1; XM_446578.1.
DR   AlphaFoldDB; Q6FT66; -.
DR   STRING; 5478.XP_446578.1; -.
DR   EnsemblFungi; CAG59505; CAG59505; CAGL0G05005g.
DR   GeneID; 2887981; -.
DR   KEGG; cgr:CAGL0G05005g; -.
DR   CGD; CAL0130793; CAGL0G05005g.
DR   VEuPathDB; FungiDB:CAGL0G05005g; -.
DR   eggNOG; ENOG502RYBU; Eukaryota.
DR   HOGENOM; CLU_1273151_0_0_1; -.
DR   InParanoid; Q6FT66; -.
DR   Proteomes; UP000002428; Chromosome G.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000184; P:nuclear-transcribed mRNA catabolic process, nonsense-mediated decay; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Cytoplasm; Nonsense-mediated mRNA decay; Reference proteome.
FT   CHAIN           1..244
FT                   /note="Nonsense-mediated decay protein 4"
FT                   /id="PRO_0000096876"
SQ   SEQUENCE   244 AA;  28254 MW;  28ABD4E4C26F5AA0 CRC64;
     MNQYNFILDA SAFEKGLGNV KRWCQSNGNV DGKKNVYLRF YVPTFTLQEL NFLQYRHKSF
     SAKEALKFID KLETATSEGQ RNHVVIGRKK EEDLRSDLEL FIEFPDILDA VTWPTVLSYC
     TEGQATIDSL NKLPKRFKIL LKSCVYKCHL EDDDRIRWIL VTEDPQVRKI ASQCHIPWCS
     IVDADSIISK DMNDRSFRDS EKFNSMMLKR GVAKSENMDG KEVIKTNFDQ TVYATRGSGK
     LWTP