ID   NMES1_MOUSE             Reviewed;          83 AA.
AC   Q810Q5;
DT   15-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=Normal mucosa of esophagus-specific gene 1 protein;
GN   Name=Nmes1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [2]
RP   TISSUE SPECIFICITY, AND DEVELOPMENTAL STAGE.
RX   PubMed=12209954; DOI=10.1002/ijc.10600;
RA   Zhou J., Wang H., Lu A., Hu G., Luo A., Ding F., Zhang J., Wang X., Wu M.,
RA   Liu Z.;
RT   "A novel gene, NMES1, downregulated in human esophageal squamous cell
RT   carcinoma.";
RL   Int. J. Cancer 101:311-316(2002).
RN   [3]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Strongly expressed in vertebrae, brain, intestine
CC       and stomach. {ECO:0000269|PubMed:12209954}.
CC   -!- DEVELOPMENTAL STAGE: First detected at 8 dpc in the ossification center
CC       and the spinal cord. From this stage up to birth, expression extends
CC       throughout the bone tissue and strong expression is detected in the
CC       vertebrae. At 16 dpc, detected in the developing brain, including the
CC       prosencephalon, mesencephalon, diencephalon, telencephalon and
CC       rhombencephalon, and in the intestine. Faint expression at 16 dpc in
CC       the lung. {ECO:0000269|PubMed:12209954}.
CC   -!- SIMILARITY: Belongs to the complex I NDUFA4 subunit family.
CC       {ECO:0000305}.
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DR   EMBL; BC049633; AAH49633.1; -; mRNA.
DR   CCDS; CCDS38224.1; -.
DR   RefSeq; NP_001004174.1; NM_001004174.1.
DR   RefSeq; XP_006499936.1; XM_006499873.3.
DR   AlphaFoldDB; Q810Q5; -.
DR   SMR; Q810Q5; -.
DR   STRING; 10090.ENSMUSP00000040781; -.
DR   iPTMnet; Q810Q5; -.
DR   PhosphoSitePlus; Q810Q5; -.
DR   EPD; Q810Q5; -.
DR   MaxQB; Q810Q5; -.
DR   PaxDb; Q810Q5; -.
DR   PRIDE; Q810Q5; -.
DR   ProteomicsDB; 253086; -.
DR   Antibodypedia; 56517; 36 antibodies from 10 providers.
DR   DNASU; 433470; -.
DR   Ensembl; ENSMUST00000047498; ENSMUSP00000040781; ENSMUSG00000033213.
DR   Ensembl; ENSMUST00000110512; ENSMUSP00000106141; ENSMUSG00000033213.
DR   GeneID; 433470; -.
DR   KEGG; mmu:433470; -.
DR   UCSC; uc008may.1; mouse.
DR   MGI; MGI:3034182; AA467197.
DR   VEuPathDB; HostDB:ENSMUSG00000033213; -.
DR   eggNOG; ENOG502STGR; Eukaryota.
DR   GeneTree; ENSGT00390000009277; -.
DR   HOGENOM; CLU_178748_0_0_1; -.
DR   InParanoid; Q810Q5; -.
DR   OMA; ANPEPWE; -.
DR   OrthoDB; 1552648at2759; -.
DR   PhylomeDB; Q810Q5; -.
DR   TreeFam; TF106383; -.
DR   BioGRID-ORCS; 433470; 1 hit in 73 CRISPR screens.
DR   ChiTaRS; AA467197; mouse.
DR   PRO; PR:Q810Q5; -.
DR   Proteomes; UP000000589; Chromosome 2.
DR   RNAct; Q810Q5; protein.
DR   Bgee; ENSMUSG00000033213; Expressed in ileum and 46 other tissues.
DR   ExpressionAtlas; Q810Q5; baseline and differential.
DR   Genevisible; Q810Q5; MM.
DR   GO; GO:0005751; C:mitochondrial respiratory chain complex IV; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0009617; P:response to bacterium; IEP:MGI.
DR   InterPro; IPR010530; B12D.
DR   PANTHER; PTHR14256; PTHR14256; 1.
DR   Pfam; PF06522; B12D; 1.
PE   1: Evidence at protein level;
KW   Nucleus; Reference proteome.
FT   CHAIN           1..83
FT                   /note="Normal mucosa of esophagus-specific gene 1 protein"
FT                   /id="PRO_0000118824"
SQ   SEQUENCE   83 AA;  9584 MW;  0550DCA98B74D941 CRC64;
     MGVFQILMKN KELIPLAFFI SVAATGATSF ALYALKKTDV VIDRKRNPEP WEMVDPTQPQ
     KLITINQQWK PVEELQKVRR ATR