ID   NMT_AMEPV               Reviewed;         299 AA.
AC   Q9EMI7;
DT   16-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Putative glycylpeptide N-tetradecanoyltransferase;
DE            EC=2.3.1.97;
DE   AltName: Full=Myristoyl-CoA:protein N-myristoyltransferase;
DE            Short=NMT;
DE   AltName: Full=Peptide N-myristoyltransferase;
GN   OrderedLocusNames=AMV219;
OS   Amsacta moorei entomopoxvirus (AmEPV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Chitovirales; Poxviridae; Entomopoxvirinae; Betaentomopoxvirus.
OX   NCBI_TaxID=28321;
OH   NCBI_TaxID=340055; Amsacta.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=10936094; DOI=10.1006/viro.2000.0449;
RA   Bawden A.L., Glassberg K.J., Diggans J., Shaw R., Farmerie W., Moyer R.W.;
RT   "Complete genomic sequence of the Amsacta moorei entomopoxvirus: analysis
RT   and comparison with other poxviruses.";
RL   Virology 274:120-139(2000).
RN   [2]
RP   POSSIBLE FUNCTION.
RX   PubMed=11955007; DOI=10.1006/jmbi.2002.5425;
RA   Maurer-Stroh S., Eisenhaber B., Eisenhaber F.;
RT   "N-terminal N-myristoylation of proteins: refinement of the sequence motif
RT   and its taxon-specific differences.";
RL   J. Mol. Biol. 317:523-540(2002).
CC   -!- FUNCTION: Adds a myristoyl group to the N-terminal glycine residue of
CC       certain proteins. {ECO:0000305}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=N-terminal glycyl-[protein] + tetradecanoyl-CoA = CoA + H(+) +
CC         N-tetradecanoylglycyl-[protein]; Xref=Rhea:RHEA:15521, Rhea:RHEA-
CC         COMP:12666, Rhea:RHEA-COMP:12667, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57287, ChEBI:CHEBI:57385, ChEBI:CHEBI:64723,
CC         ChEBI:CHEBI:133050; EC=2.3.1.97;
CC   -!- SIMILARITY: Belongs to the NMT family. {ECO:0000305}.
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DR   EMBL; AF250284; AAG02925.1; -; Genomic_DNA.
DR   RefSeq; NP_065001.1; NC_002520.1.
DR   SMR; Q9EMI7; -.
DR   GeneID; 1494809; -.
DR   KEGG; vg:1494809; -.
DR   Proteomes; UP000000872; Genome.
DR   GO; GO:0004379; F:glycylpeptide N-tetradecanoyltransferase activity; IEA:UniProtKB-EC.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR022676; NMT_N.
DR   Pfam; PF01233; NMT; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
PE   3: Inferred from homology;
KW   Acyltransferase; Reference proteome; Transferase.
FT   CHAIN           1..299
FT                   /note="Putative glycylpeptide N-tetradecanoyltransferase"
FT                   /id="PRO_0000064249"
SQ   SEQUENCE   299 AA;  36429 MW;  FCEC2E31D7D06F68 CRC64;
     MSYWINKSIC KLNYDSIDNI INTIEPHKPY NNNYCKDNFN IKYLDENNIL DYYSFLYKNY
     NYKFNLDTIK WLLLNPFSKK EYNILLYNED KIAGTISGIK KTISLHKKIY DCIHVTFLCI
     DKDYRNKYLH YFLIDEIMKN AKKNDIIIAL FNSNIKFNNV KYINEYDTYI TYGNKNLIKK
     SDYFNYELLN KKTQDLFFIY TIEEYNYWFN NNHVVVISYN NNFIALLKTN MLINKNIIQI
     FIIMEMYIRN NNIHKNYIPN NTIIYENYKC LKTIKLKSKL ISYIYNYNFN NLSESIYLF