NNAT_BOVIN
ID NNAT_BOVIN Reviewed; 81 AA.
AC Q3ZBS9; Q6UTX8; Q9GMZ0;
DT 29-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 73.
DE RecName: Full=Neuronatin;
GN Name=NNAT;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM ALPHA).
RC STRAIN=Hereford; TISSUE=Fetal liver;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA).
RA Hahn Y., Chung J.H.;
RT "Bos taurus neuronatin beta.";
RL Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 14-81 (ISOFORM ALPHA).
RX PubMed=14668210; DOI=10.1095/biolreprod.103.022236;
RA Ruddock N.T., Wilson K.J., Cooney M.A., Korfiatis N.A., Tecirlioglu R.T.,
RA French A.J.;
RT "Analysis of imprinted messenger RNA expression during bovine
RT preimplantation development.";
RL Biol. Reprod. 70:1131-1135(2004).
CC -!- FUNCTION: May participate in the maintenance of segment identity in the
CC hindbrain and pituitary development, and maturation or maintenance of
CC the overall structure of the nervous system. May function as a
CC regulatory subunit of ion channels (By similarity). {ECO:0000250}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=Alpha;
CC IsoId=Q3ZBS9-1; Sequence=Displayed;
CC Name=Beta;
CC IsoId=Q3ZBS9-2; Sequence=VSP_025881;
CC -!- SIMILARITY: Belongs to the neuronatin family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BC103128; AAI03129.1; -; mRNA.
DR EMBL; AB047030; BAB08220.1; -; mRNA.
DR EMBL; AY360450; AAR12962.1; -; mRNA.
DR RefSeq; NP_001188253.1; NM_001201324.1. [Q3ZBS9-1]
DR RefSeq; NP_847893.1; NM_178323.3. [Q3ZBS9-2]
DR AlphaFoldDB; Q3ZBS9; -.
DR STRING; 9913.ENSBTAP00000004170; -.
DR PaxDb; Q3ZBS9; -.
DR PRIDE; Q3ZBS9; -.
DR Ensembl; ENSBTAT00000004170; ENSBTAP00000004170; ENSBTAG00000003212. [Q3ZBS9-1]
DR Ensembl; ENSBTAT00000004171; ENSBTAP00000004171; ENSBTAG00000003212. [Q3ZBS9-2]
DR GeneID; 353114; -.
DR KEGG; bta:353114; -.
DR CTD; 4826; -.
DR VEuPathDB; HostDB:ENSBTAG00000003212; -.
DR eggNOG; ENOG502TDP2; Eukaryota.
DR GeneTree; ENSGT00390000007412; -.
DR HOGENOM; CLU_152636_0_0_1; -.
DR InParanoid; Q3ZBS9; -.
DR OMA; VMGERRQ; -.
DR OrthoDB; 1518314at2759; -.
DR TreeFam; TF338710; -.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000003212; Expressed in adenohypophysis and 105 other tissues.
DR GO; GO:0005737; C:cytoplasm; IBA:GO_Central.
DR GO; GO:0007420; P:brain development; IBA:GO_Central.
DR GO; GO:0032024; P:positive regulation of insulin secretion; IBA:GO_Central.
DR InterPro; IPR024885; Neuronatin.
DR PANTHER; PTHR15285; PTHR15285; 1.
PE 3: Inferred from homology;
KW Alternative splicing; Developmental protein; Reference proteome.
FT CHAIN 1..81
FT /note="Neuronatin"
FT /id="PRO_0000289055"
FT VAR_SEQ 25..51
FT /note="Missing (in isoform Beta)"
FT /evidence="ECO:0000303|Ref.2"
FT /id="VSP_025881"
SQ SEQUENCE 81 AA; 9246 MW; 067086D85B3E3D20 CRC64;
MAAVAAASAE LLIIGWYIFR VLLQVFLECC IYWVGFAFRN PPGTQPIARS EVFRYSLQKL
AYTVSRTGRH VLGERRQRAP N