ID   NO12_MEDTR              Reviewed;         103 AA.
AC   P30365;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Early nodulin-12;
DE            Short=N-12;
DE   Flags: Precursor;
GN   Name=ENOD12;
OS   Medicago truncatula (Barrel medic) (Medicago tribuloides).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC   NPAAA clade; Hologalegina; IRL clade; Trifolieae; Medicago.
OX   NCBI_TaxID=3880;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=cv. Jemalong;
RX   PubMed=1446169; DOI=10.2307/3869407;
RA   Pichon M., Journet E.-P., Dedieu A., de Billy F., Truchet G., Barker D.G.;
RT   "Rhizobium meliloti elicits transient expression of the early nodulin gene
RT   ENOD12 in the differentiating root epidermis of transgenic alfalfa.";
RL   Plant Cell 4:1199-1211(1992).
CC   -!- FUNCTION: Involved in the infection process during the plant-rhizobium
CC       interaction.
CC   -!- SUBCELLULAR LOCATION: Secreted, cell wall {ECO:0000305}.
CC   -!- TISSUE SPECIFICITY: Root nodules.
CC   -!- INDUCTION: By soluble compounds from rhizobium (in cells through which
CC       the infection thread is migrating and also in cells that do not yet
CC       contain an infection thread).
CC   -!- SIMILARITY: Belongs to the plant proline-rich protein superfamily.
CC       ENOD12 family. {ECO:0000305}.
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DR   EMBL; X68032; CAA48173.1; -; Genomic_DNA.
DR   PIR; JQ1668; JQ1668.
DR   RefSeq; XP_013459222.1; XM_013603768.1.
DR   AlphaFoldDB; P30365; -.
DR   EnsemblPlants; KEH33031; KEH33031; MTR_3g415650.
DR   GeneID; 25490361; -.
DR   Gramene; KEH33031; KEH33031; MTR_3g415650.
DR   HOGENOM; CLU_2267739_0_0_1; -.
DR   ExpressionAtlas; P30365; differential.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0009877; P:nodulation; IEA:UniProtKB-KW.
PE   2: Evidence at transcript level;
KW   Cell wall; Nodulation; Repeat; Secreted; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..103
FT                   /note="Early nodulin-12"
FT                   /id="PRO_0000019803"
FT   REPEAT          34..38
FT                   /note="1"
FT   REPEAT          39..43
FT                   /note="2"
FT   REPEAT          44..48
FT                   /note="3; approximate"
FT   REPEAT          49..53
FT                   /note="4"
FT   REPEAT          54..58
FT                   /note="5"
FT   REPEAT          59..63
FT                   /note="6"
FT   REPEAT          64..68
FT                   /note="7"
FT   REPEAT          69..73
FT                   /note="8"
FT   REPEAT          74..78
FT                   /note="9"
FT   REPEAT          79..83
FT                   /note="10; approximate"
FT   REPEAT          84..88
FT                   /note="11"
FT   REGION          34..103
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          34..88
FT                   /note="11 X 5 AA approximate tandem repeats of P-P-[QVHR]-
FT                   [TNKH]-[KED]"
FT   COMPBIAS        34..48
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..103
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   103 AA;  11744 MW;  C207B8B2908A1592 CRC64;
     MASFSLSILV FFFSALVLVP QGFAEYYLYP AYRPPQTKPP VNKPSHKEPP VNKPPHKEPP
     VHKPPHKDPP VNKPPQKESP VHKPPRKESP THRHPPAEDN IHF