ID   NOC1_CHATD              Reviewed;        1042 AA.
AC   G0SEQ5;
DT   16-MAR-2016, integrated into UniProtKB/Swiss-Prot.
DT   16-MAR-2016, sequence version 2.
DT   25-MAY-2022, entry version 39.
DE   RecName: Full=Ribosome biogenesis protein NOC1;
DE   AltName: Full=Nucleolar complex protein 1;
GN   Name=NOC1; ORFNames=CTHT_0059330;
OS   Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Sordariomycetidae; Sordariales; Chaetomiaceae; Chaetomium.
OX   NCBI_TaxID=759272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 1495 / CBS 144.50 / IMI 039719;
RX   PubMed=21784248; DOI=10.1016/j.cell.2011.06.039;
RA   Amlacher S., Sarges P., Flemming D., van Noort V., Kunze R., Devos D.P.,
RA   Arumugam M., Bork P., Hurt E.;
RT   "Insight into structure and assembly of the nuclear pore complex by
RT   utilizing the genome of a eukaryotic thermophile.";
RL   Cell 146:277-289(2011).
CC   -!- FUNCTION: Required for 60S ribosomal subunit synthesis.
CC       {ECO:0000250|UniProtKB:Q12176}.
CC   -!- SUBUNIT: Interacts with NOC2. Forms a nucleolar complex with NOC2 that
CC       binds to 90S and 66S pre-ribosomes. {ECO:0000250|UniProtKB:Q12176}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC       {ECO:0000250|UniProtKB:Q12176}.
CC   -!- SIMILARITY: Belongs to the CBF/MAK21 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=EGS17921.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; GL988046; EGS17921.1; ALT_SEQ; Genomic_DNA.
DR   RefSeq; XP_006696252.1; XM_006696189.1.
DR   AlphaFoldDB; G0SEQ5; -.
DR   STRING; 759272.G0SEQ5; -.
DR   EnsemblFungi; EGS17921; EGS17921; CTHT_0059330.
DR   GeneID; 18259971; -.
DR   KEGG; cthr:CTHT_0059330; -.
DR   eggNOG; KOG2038; Eukaryota.
DR   HOGENOM; CLU_003417_0_0_1; -.
DR   OrthoDB; 551907at2759; -.
DR   Proteomes; UP000008066; Unassembled WGS sequence.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   GO; GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
DR   Gene3D; 1.25.10.10; -; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR005612; CCAAT-binding_factor.
DR   InterPro; IPR040155; CEBPZ/Mak21-like.
DR   PANTHER; PTHR12048; PTHR12048; 1.
DR   Pfam; PF03914; CBF; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   3: Inferred from homology;
KW   Nucleus; Reference proteome; Ribosome biogenesis.
FT   CHAIN           1..1042
FT                   /note="Ribosome biogenesis protein NOC1"
FT                   /id="PRO_0000435813"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          28..79
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          101..128
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          148..214
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          546..567
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          897..1020
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        38..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        114..128
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        176..190
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        191..214
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        897..914
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        922..937
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        938..957
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1042 AA;  114781 MW;  D88756E89079D36F CRC64;
     MGLKRAARQQ RDIGKPAFDE EALVELTGKI DKTLPAVEQK IAGKRKRQNA SDDGRGSKRR
     QTHPTEAEEH RDSHAAAKDK ANRILLEEII ALGGDEKDLE LVADVDSGNE GGGGPSQPKI
     SSEQSLDQSF KDELAKFAAS LGFHQFHNRE DLNTEDEASP DEDAVGSTTD VSSDSDEGGG
     QEEMEKEDVD SFSDNEEKVT EKVDSGEAKI IPQDTKKGKQ FRNLIIDPRP DWHAFPLDEL
     PASRPDHPGK YSASIANLKS YAESLLEEDT ANYQSAQAHS STRKFMSTIM SSGTLSDKIS
     ALTLSIQESP LHNRKAFESL ITLAGKKNRG QAIAALGALV DLLGNGAVLP DDRRLRPFGG
     QPALFGALQG SASQTWVAGQ TLPGKLTKAH LVMWAYEDWL KAAYFRIIQL LEVWCSDEIE
     YSRSRALDFV FGLLKNKPEQ EANLLRLLVN KLGDRERKIA SRASYLLLQL LNVHPGMKGI
     VIGTVEQEVL LKPGQSLRTK YTAINTLNQT ILSTREPSIA DKLLRIYFDM FLALLKSGVL
     GNVGALNGDK RDGGTPRKKS NPSGSLTVGN EQDVAQKLVS ALLTGVNRAI PFATTEDSTL
     EKHLDTLFRI THSSNFNTSI QALMLIQQLA TSKQLAVDRF YRTLYESLLD PRLVTSSKHA
     LYLNLIFRAM KNDADVRRVK AFVKRLIQIL TLHQPSFTCG VLFLISELQK TFPDLRTLLD
     DPEEADDDGE EVYKDVCEDG TLDNVETQGV TSSFVSPATA YDGRKRDPEH SNAHRSCLWE
     LTPLLSHYHP SVGIFARNLL SPQQSLPKPD LAHHTLMHFL DKFVYRNPKA EETKRGGSIM
     QPVLASGGTS RIVVSSKAAA KQQQSVNSAS FWNLKPEQVL AEDVFFHEYF TRIGKPGKMT
     RKRDETKREF GSGDETGDED EIWDALVKSK PDVEGPNVDD DSDADLGDFD YSDDEEDGSR
     TDGSMSDIGM DSDGFEGIFD DAGESDEQSS GEDEAPTKAK KGTATSGQKG RLSKKELKTL
     PTFASAEDYA DILAAEDDGL DD