ID   NOC3L_PONAB             Reviewed;         800 AA.
AC   Q5R952;
DT   27-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   21-DEC-2004, sequence version 1.
DT   25-MAY-2022, entry version 60.
DE   RecName: Full=Nucleolar complex protein 3 homolog;
DE            Short=NOC3 protein homolog;
DE   AltName: Full=NOC3-like protein;
DE   AltName: Full=Nucleolar complex-associated protein 3-like protein;
GN   Name=NOC3L;
OS   Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Pongo.
OX   NCBI_TaxID=9601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Brain cortex;
RG   The German cDNA consortium;
RL   Submitted (NOV-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be required for adipogenesis. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus speckle
CC       {ECO:0000250}. Note=Localizes to nuclear speckles. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the CBF/MAK21 family. {ECO:0000305}.
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DR   EMBL; CR859543; CAH91708.1; -; mRNA.
DR   RefSeq; NP_001127453.1; NM_001133981.1.
DR   AlphaFoldDB; Q5R952; -.
DR   SMR; Q5R952; -.
DR   STRING; 9601.ENSPPYP00000002897; -.
DR   GeneID; 100174525; -.
DR   KEGG; pon:100174525; -.
DR   CTD; 64318; -.
DR   eggNOG; KOG2153; Eukaryota.
DR   InParanoid; Q5R952; -.
DR   OrthoDB; 341721at2759; -.
DR   Proteomes; UP000001595; Unplaced.
DR   GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR   GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR005612; CCAAT-binding_factor.
DR   InterPro; IPR011501; Noc3_N.
DR   InterPro; IPR016903; Nucleolar_cplx-assoc_3.
DR   PANTHER; PTHR14428; PTHR14428; 1.
DR   Pfam; PF03914; CBF; 1.
DR   Pfam; PF07540; NOC3p; 1.
DR   PIRSF; PIRSF028977; Nucleolar_complex_p3; 1.
DR   SUPFAM; SSF48371; SSF48371; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Isopeptide bond; Nucleus; Phosphoprotein; Reference proteome;
KW   Ubl conjugation.
FT   CHAIN           1..800
FT                   /note="Nucleolar complex protein 3 homolog"
FT                   /id="PRO_0000173476"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          160..187
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          451..490
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        38..81
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         787
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WTT2"
FT   CROSSLNK        333
FT                   /note="Glycyl lysine isopeptide (Lys-Gly) (interchain with
FT                   G-Cter in SUMO2)"
FT                   /evidence="ECO:0000250|UniProtKB:Q8WTT2"
SQ   SEQUENCE   800 AA;  92439 MW;  D33F0ED16FF9252B CRC64;
     MKARRNKKQI PSFRKLIKTS KVKPENKLKN KQFKQQSTLK KYRKEQRKLR QAVKDAVSKK
     PIPLENPKEK RPGKRIEREE EEEEEALPLD MMDEDDLQLM KDLGQRASFL TRDLSSSEPV
     HAKKRKHKRI IDKYEKIPRT LQTVPEKELI HLLPIKDKSG IIPQTREKPV TDSNKDEEDQ
     EEERELEEEI IEDPIQELTI EEHLIERKKK LQEKKMHIAA LASAILSDPE SNIKKLKELR
     SMLMEQDPDV AVTVRKLVIV SLMELFKDIT PSYKIRPLTE AEKSTKTRKE TQKLREFEEG
     LVSQYKFYLE NLEQMVKDWK QRKLKKSNVV SLKAYKGLAE VAVKSLCELL VALPHFNFHN
     NIIVLIVPLM NDMSKSISEM CCEAVKKLFK QDKLGQASLG VIKVISGFVK GRKYEVRPEM
     LKTFLCLRIK EVEVKKDTED INKPKKFMTF KEKRKSLSRM QRKWKKAEEK LERELREAEA
     SESTEKKLKL HTETLNIVFV TYFRILKKAQ RSPLLPAVLE GLAKFAHLIN VEFFDDLLVV
     LHTLIESGDL SYKESLHCVQ TAFHILSGQG DVLNIDPMKF YTHLYKTLFK LHAGATNEGV
     EIVLQCLDVM LTKRRKQVSQ QRALAFIKRL CTLALHVLPN SSIGILATTR ILMHTFPKTD
     LLLDSESQGS GVFLPELDEP EYCNAQNTAL WELHALRRHY HPIVQRFAVH LIAGAPSEGS
     GALKPELSRR SAAELFEAYS TAEMTFNPPV ESSNPKIKGK VLQGDSFLNE DLNHLIKRYS
     SEVATESPLD FTKYLKTSLH